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  1. The investigation of glycated hemoglobin (HbA1c) as a diagnostic tool for abnormal glycometabolism is lack in acute ischemic stroke patients in China and worldwide. This paper was aimed to determine whether Hb...

    Authors: Shuolin Wu, Yuzhi Shi, Yuesong Pan, Jingjing Li, Qian Jia, Ning Zhang, Xingquan Zhao, Gaifen Liu, Yilong Wang, Yongjun Wang and Chunxue Wang
    Citation: BMC Neurology 2014 14:177
    Content type: Research article Published on:

  2. Dementia has been associated with an increased risk of hip fracture. However, little research has been conducted on the impact of dementia on wrist or vertebral fracture development. The aim of this study was ...

    Authors: Hao-Kuang Wang, Chao-Ming Hung, Sheng-Hsiang Lin, Yi-Cheng Tai, Kang Lu, Po-Chou Liliang, Chi-Wei Lin, Yi-Che Lee, Pei-Hsuan Fang, Li-Ching Chang and Ying-Chun Li
    Citation: BMC Neurology 2014 14:175
    Content type: Research article Published on:

  3. Following carotid revascularization, an abrupt increase in cerebral blood flow may disrupt the blood-brain barrier, resulting in reperfusion injury. This damage to the blood-brain barrier may be reflected by s...

    Authors: Hyun-Ji Cho, Young Jin Kim, Joon Hwa Lee, Jin Woo Choi, Won-Jin Moon, Hong Gee Roh, Young Il Chun and Hahn Young Kim
    Citation: BMC Neurology 2014 14:178
    Content type: Case report Published on:

  5. BICAMS (Brief International Cognitive Assessment for Multiple Sclerosis) has been recently developed as brief, practical and universal assessment tool for cognitive impairment in MS subjects. It includes the S...

    Authors: Benedetta Goretti, Claudia Niccolai, Bahia Hakiki, Andrea Sturchio, Monica Falautano, Eleonora Minacapelli, Vittorio Martinelli, Chiara Incerti, Ugo Nocentini, Monica Murgia, Giuseppe Fenu, Eleonora Cocco, Maria Giovanna Marrosu, Elisabetta Garofalo, Ferdinando Ivano Ambra, Maurizio Maddestra…
    Citation: BMC Neurology 2014 14:171
    Content type: Research article Published on:

  6. The failures of recent studies intended to prevent cerebral vasospasm have moved the focus of research into delayed cerebral ischemia away from cerebral artery constriction towards other mechanisms. Recent acc...

    Authors: Satoru Takeuchi, Kentaro Mori, Hirohiko Arimoto, Kazuya Fujii, Kimihiro Nagatani, Satoshi Tomura, Naoki Otani, Hideo Osada and Kojiro Wada
    Citation: BMC Neurology 2014 14:176
    Content type: Study protocol Published on:

  7. Creutzfeldt-Jakob disease and Hashimoto's encephalopathy often show similar clinical presentation. Among Creutzfeldt-Jakob disease mimics, Hashimoto's encephalopathy is particularly important as it is treatabl...

    Authors: Jae-Won Jang, So Young Park, Young Ho Park, Jung E Kim and SangYun Kim
    Citation: BMC Neurology 2014 14:179
    Content type: Case report Published on:

  8. There is uncertainty surrounding the differences in outcomes after intracerebral haemorrhage (ICH) between men and women. This study aimed to investigate the sex differences in clinical characteristics, severi...

    Authors: Junshan Zhou, Yingdong Zhang, Hisatomi Arima, Yanxia Zhao, Hongdong Zhao, Danni Zheng, Youyong Tian, Yukai Liu, Qing Huang and Jie Yang
    Citation: BMC Neurology 2014 14:172
    Content type: Research article Published on:

  9. High frequency repetitive transcranial magnetic stimulation (rTMS) targetted to different cortical regions (primary motor/sensory, prefrontal) are known to alter somatosensory responses. The mechanism(s) for t...

    Authors: Paul Sacco, Michael Prior, Helen Poole and Turo Nurmikko
    Citation: BMC Neurology 2014 14:166
    Content type: Research article Published on:

  12. A key treatment for acute ischaemic stroke is thrombolysis (rtPA). However, treatment is not devoid of side effects and patients are carefully selected. AVERT (A Very Early Rehabilitation Trial), a large, ongo...

    Authors: Linnéa Muhl, Jenny Kulin, Marie Dagonnier, Leonid Churilov, Helen Dewey, Thomas Lindén and Julie Bernhardt
    Citation: BMC Neurology 2014 14:163
    Content type: Research article Published on:

  13. There are inconsistent reports about multiple sclerosis (MS) risk among migrants from low to high MS risk geographical regions. This study assessed the overall MS incidence and evaluated seasonality in birth a...

    Authors: Saeed Akhtar, Raed Alroughani, Ahmad Al-Shammari, Jarrah Al-Abkal and Yasser Ayad
    Citation: BMC Neurology 2014 14:170
    Content type: Research article Published on:

  14. The objectives of this study were to explore the relationship between olfactory impairment, cognitive measures, and brain structure volumes in healthy elderly individuals, compared to patients with amnestic mi...

    Authors: Grete Kjelvik, Ingvild Saltvedt, Linda R White, Pål Stenumgård, Olav Sletvold, Knut Engedal, Kristina Skåtun, Ann Kristin Lyngvær, Hill Aina Steffenach and Asta K Håberg
    Citation: BMC Neurology 2014 14:168
    Content type: Research article Published on:

  15. Patients suffering from Multiple Sclerosis (MS) experience a wide array of symptoms, including balance problems, mobility impairment, fatigue and depression. Physical exercise has recently been acknowledged as...

    Authors: Janina M Burschka, Philipp M Keune, Ulrich Hofstadt-van Oy, Patrick Oschmann and Peter Kuhn
    Citation: BMC Neurology 2014 14:165
    Content type: Research article Published on:

  16. There is increasing evidence for the beneficial effects of exercise training in stroke survivors. In order to reach the desired training effects, exercise training principles must be considered as this ensures...

    Authors: Bernadette C Ammann, Ruud H Knols, Pierrette Baschung, Rob A de Bie and Eling D de Bruin
    Citation: BMC Neurology 2014 14:167
    Content type: Research article Published on:

  17. Fingolimod is a disease modifying therapy (DMT) in highly active relapsing remitting multiple sclerosis (RRMS), as is natalizumab. Fingolimod decreases annual relapse rates and gadolinium enhancing lesions on ...

    Authors: Anne-Hilde Muris, Linda Rolf, Jan Damoiseaux, Ellen Koeman and Raymond Hupperts
    Citation: BMC Neurology 2014 14:164
    Content type: Case report Published on:

  18. Neuromyelitis optica spectrum disorder (NMOSD) can coexist with non-organ-specific or organ-specific autoimmune diseases. The aim of this study was to investigate and compare the features between NMOSD without...

    Authors: Bingjun Zhang, Yi Zhong, Yanqiang Wang, Yongqiang Dai, Wei Qiu, Lei Zhang, Haiyan Li and Zhengqi Lu
    Citation: BMC Neurology 2014 14:162
    Content type: Research article Published on:

  19. Autosomal recessive limb-girdle muscular dystrophies (LGMD2) include a number of disorders with heterogeneous etiology that cause predominantly weakness and wasting of the shoulder and pelvic girdle muscles. I...

    Authors: Kristýna Stehlíková, Daniela Skálová, Jana Zídková, Lenka Mrázová, Petr Vondráček, Radim Mazanec, Stanislav Voháňka, Jana Haberlová, Markéta Hermanová, Josef Zámečník, Ondřej Souček, Hana Ošlejšková, Nina Dvořáčková, Pavla Solařová and Lenka Fajkusová
    Citation: BMC Neurology 2014 14:154
    Content type: Research article Published on:

  20. Electroencephalography (EEG) is widely used to assess neurological prognosis in patients who are comatose after cardiac arrest, but its value is limited by varying definitions of pathological patterns and by i...

    Authors: Erik Westhall, Ingmar Rosén, Andrea O Rossetti, Anne-Fleur van Rootselaar, Troels Wesenberg Kjaer, Janneke Horn, Susann Ullén, Hans Friberg, Niklas Nielsen and Tobias Cronberg
    Citation: BMC Neurology 2014 14:159
    Content type: Study protocol Published on:

  21. Epilepsy is common in patients with a glioma. Antiepileptic drugs (AEDs) are the mainstay of epilepsy treatment, but may cause side effects and may negatively impact neurocognitive functioning and quality of l...

    Authors: Johan A F Koekkoek, Melissa Kerkhof, Linda Dirven, Jan J Heimans, Tjeerd J Postma, Maaike J Vos, Jacoline E C Bromberg, Martin J van den Bent, Jaap C Reijneveld and Martin J B Taphoorn
    Citation: BMC Neurology 2014 14:157
    Content type: Study protocol Published on:

  22. Intracranial Atherosclerotic Disease (ICAD) is the most frequent etiology of stroke with high prevalence among Asians. Despite this, early determinants of ICAD have not been described from this region.

    Authors: Ayeesha Kamran Kamal, Farzin Majeed, Omrana Pasha, Hasan Rehman, Muhammad Islam, Iqbal Azam, Muhammad Saleem Ilyas, Munawar Hussain, Kamran Masood, Bilal Ahmed, Sumaira Nazir, Zafar Sajjad and Scott E Kasner
    Citation: BMC Neurology 2014 14:155
    Content type: Research article Published on:

  23. Pisa Syndrome or Pleurothotonus is a relatively rare truncal dystonia, characterized by tonic flexion of the trunk and head to one side with slight rotation of the body. Since frequently associated to specific...

    Authors: Pasquale Marchione, Aldo Spallone, Marcella Valente, Cristiano Giannone, Floriana De Angelis and Giuseppe Meco
    Citation: BMC Neurology 2014 14:149
    Content type: Case report Published on:

  24. Meningeal carcinomatosis and hypercoagulability associated with malignancy are typical late stage complications in cancer patients. The co-occurrence of meningeal carcinomatosis and cerebral infarction related...

    Authors: Akiko Kawasaki, Keisuke Suzuki, Hidehiro Takekawa, Toshiki Nakamura, Masanari Yamamoto, Yohei Asakawa, Madoka Okamura and Koichi Hirata
    Citation: BMC Neurology 2014 14:160
    Content type: Case report Published on:

  25. Cerebral cavernous malformations are relatively rare vascular disorders that may affect any part of the central nervous system. This presentation has been associated with heterozygous mutations in CCM1/KRIT1, CCM...

    Authors: Silvia Lanfranconi, Dario Ronchi, Naghia Ahmed, Vittorio Civelli, Paola Basilico, Nereo Bresolin, Giacomo Pietro Comi and Stefania Corti
    Citation: BMC Neurology 2014 14:158
    Content type: Case report Published on:

  27. Osteogenesis imperfecta (OI) is a heterogeneous group of inherited disorders that occur owing to the abnormalities in type 1 collagen, and is characterized by increased bone fragility and other extraskeletal m...

    Authors: Toshio Hirohata, Satoru Miyawaki, Akiko Mizutani, Takayuki Iwakami, So Yamada, Hajime Nishido, Yasutaka Suzuki, Shinya Miyamoto, Katsumi Hoya, Mineko Murakami and Akira Matsuno
    Citation: BMC Neurology 2014 14:150
    Content type: Case report Published on:

  28. The cognitive consequences of carbon monoxide (CO) poisoning are well described. However, most studies have been carried out without an ad-hoc group of control subjects. The main aim of this study was to evalu...

    Authors: Bérengère Pages, Mélanie Planton, Sophie Buys, Béatrice Lemesle, Philippe Birmes, Emmanuel Joseph Barbeau, Stéphanie Maziero, Laurie Cordier, Claudine Cabot, Michèle Puel, Michèle Genestal, François Chollet and Jérémie Pariente
    Citation: BMC Neurology 2014 14:153
    Content type: Research article Published on:

  29. The Kii peninsula of Japan is one of the foci of amyotrophic lateral sclerosis and parkinsonism-dementia complex (ALS/PDC) in the world. The purpose of this study is to clarify the neuropsychological features ...

    Authors: Akihiro Shindo, Yukito Ueda, Shigeki Kuzuhara and Yasumasa Kokubo
    Citation: BMC Neurology 2014 14:151
    Content type: Research article Published on:

  30. Status epilepticus (SE) is a medical emergency with high mortality rates. Of all SE’s, 7% are caused by a brain tumor. Clinical guidelines on the management of SE do not make a distinction between tumor-relate...

    Authors: Yunus Arik, Frans SS Leijten, Tatjana Seute, Pierre A Robe and Tom J Snijders
    Citation: BMC Neurology 2014 14:152
    Content type: Research article Published on:

  31. Status epilepticus (SE) may occur in the setting of several internal or neurologic diseases. Anti-neutrophilic cytoplasmic antibodies (ANCA) are a group of Ig that may be observed in patients with different au...

    Authors: Edoardo Ferlazzo, Antonio Gambardella, Marina Bellavia, Sara Gasparini, Laura Mumoli, Angelo Labate, Vittoria Cianci, Concetta Russo and Umberto Aguglia
    Citation: BMC Neurology 2014 14:148
    Content type: Case report Published on:

  32. Visual fixation plays a key role in the differentiation between vegetative state/unresponsive wakefulness (VS/UWS) syndrome and minimally conscious state (MCS). However, the use of different stimuli changes th...

    Authors: Haibo Di, Yunzhi Nie, Xiaohua Hu, Yong Tong, Lizette Heine, Sarah Wannez, Wangshan Huang, Dan Yu, Minhui He, Aurore Thibaut, Caroline Schnakers and Steven Laureys
    Citation: BMC Neurology 2014 14:147
    Content type: Research article Published on:

  33. Mutations in proline-rich transmembrane protein 2 (PRRT2) are a cause of paroxysmal kinesigenic dyskinesia (PKD). In this study, we investigated the PRRT2 gene mutation in a Chinese Han family with PKD and study ...

    Authors: Zhisong Ji, Quanxi Su, Lingling Hu, Qi Yang, Cuixian Liu, Jun Xiong and Fu Xiong
    Citation: BMC Neurology 2014 14:146
    Content type: Research article Published on:

  34. The number of patients with cognitive impairment after sepsis or septic shock is high. However, the underlying neurophysiological basis of sepsis induced cognitive impairment is not fully understood.

    Authors: Theresa Götz, Albrecht Günther, Otto W Witte, Frank M Brunkhorst, Gundula Seidel and Farsin Hamzei
    Citation: BMC Neurology 2014 14:145
    Content type: Study protocol Published on:

  35. Cerebral palsy (CP) and brain injury (BI) are common conditions that have devastating effects on a child’s ability to use their hands. Hand splinting and task-specific training are two interventions that are o...

    Authors: Michelle Jackman, Iona Novak and Natasha Lannin
    Citation: BMC Neurology 2014 14:144
    Content type: Study protocol Published on:

  36. Multiple Sclerosis (MS) is a common neurodegenerative disease, which often has a devastating effect on physical and emotional wellbeing of people with MS (PwMS). Several studies have shown positive effects of ...

    Authors: Claudia H Marck, Emily J Hadgkiss, Tracey J Weiland, Dania M van der Meer, Naresh G Pereira and George A Jelinek
    Citation: BMC Neurology 2014 14:143
    Content type: Research article Published on:

  37. Since there has been no conclusive evidence regarding the treatment of ocular myasthenia, treatment guidelines were recently issued by the European Federation of Neurological Societies/European Neurological So...

    Authors: Shigeaki Suzuki, Hiroyuki Murai, Tomihiro Imai, Yuriko Nagane, Masayuki Masuda, Emiko Tsuda, Shingo Konno, Satoru Oji, Shunya Nakane, Masakatsu Motomura, Norihiro Suzuki and Kimiaki Utsugisawa
    Citation: BMC Neurology 2014 14:142
    Content type: Research article Published on:

  38. Hypertensive putaminal haemorrhage comprises major part of intra-cerebral haemorrhages, with particularly high morbidity and mortality. However, the optimal treatments for these individuals remain controversial.

    Authors: Hao Liu, Yunhui Zen, Jin Li, Xiang Wang, Hao Li, Jianguo Xu and Chao You
    Citation: BMC Neurology 2014 14:141
    Content type: Research article Published on:

  39. Subarachnoid hemorrhage (SAH) is mainly caused by ruptured cerebral aneurysms but in up to 15% of patients with SAH no bleeding source could be identified. Our objective was to analyze patient characteristics,...

    Authors: Juergen Konczalla, Johannes Platz, Patrick Schuss, Hartmut Vatter, Volker Seifert and Erdem Güresir
    Citation: BMC Neurology 2014 14:140
    Content type: Research article Published on:

  40. Cell-based assays for neuromyelitis optica (NMO) diagnosis are the most sensitive and specific methods to detect anti-aquaporin 4 (AQP4) antibodies in serum, but some improvements in their quantitative and spe...

    Authors: Ismael Sánchez Gomar, María Díaz Sánchez, Antonio José Uclés Sánchez, José Luis Casado Chocán, Reposo Ramírez-Lorca, Ana Serna, Javier Villadiego, Juan José Toledo-Aral and Miriam Echevarría
    Citation: BMC Neurology 2014 14:139
    Content type: Research article Published on:

  41. Neurocysticercosis is a major cause of neurological symptoms in developing countries. We report a case of cerebral neurocysticercosis presenting as episodic migraine without aura, with clinico-radiological cor...

    Authors: Yannick Fogoum Fogang, Massaman Camara, Amadou Gallo Diop and Mansour Mouhamadou Ndiaye
    Citation: BMC Neurology 2014 14:138
    Content type: Case report Published on:

  42. Women die of stroke more often than men. After menopause, the incidence of ischemic stroke increases rapidly. Elevated fibrinogen levels and smoking have been associated with an increased risk of stroke. In ge...

    Authors: Mika Martiskainen, Niku Oksala, Tarja Pohjasvaara, Markku Kaste, Anni Oksala, Pekka J Karhunen and Timo Erkinjuntti
    Citation: BMC Neurology 2014 14:137
    Content type: Research article Published on:

  43. Pathogenic autoantibodies targeting the recently identified leucine rich glioma inactivated 1 protein and the subunit 1 of the N-methyl-D-aspartate receptor induce autoimmune encephalitis. A comparison of brai...

    Authors: Florian Wegner, Florian Wilke, Peter Raab, Said Ben Tayeb, Anna-Lena Boeck, Cathleen Haense, Corinna Trebst, Elke Voss, Christoph Schrader, Frank Logemann, Jörg Ahrens, Andreas Leffler, Rea Rodriguez-Raecke, Reinhard Dengler, Lilli Geworski, Frank M Bengel…
    Citation: BMC Neurology 2014 14:136
    Content type: Research article Published on:

  44. We analyzed the frequency of heart rate (HR) changes related to seizures, and we sought to identify the influencing factors of these changes during partial seizures, to summarize the regularity of the HR chang...

    Authors: Wei Chen, Chang-Li Guo, Pei-Song Zhang, Chong Liu, Hui Qiao, Jian-Guo Zhang and Fan-Gang Meng
    Citation: BMC Neurology 2014 14:135
    Content type: Research article Published on:

  45. The modified version of the Postural Assessment Scale for Stroke Patients (SwePASS) is a new ordinal outcome measurement designed to assess postural control in patients with stroke. Before implementation of Sw...

    Authors: Carina U Persson, Katharina S Sunnerhagen and Åsa Lundgren-Nilsson
    Citation: BMC Neurology 2014 14:134
    Content type: Research article Published on:

  46. Previous research has suggested that vitamin D and sunlight are related to cardiovascular outcomes, but associations between sunlight and risk factors have not been investigated. We examined whether increased ...

    Authors: Shia T Kent, Mary Cushman, George Howard, Suzanne E Judd, William L Crosson, Mohammad Z Al-Hamdan and Leslie A McClure
    Citation: BMC Neurology 2014 14:133
    Content type: Research article Published on:

  47. Successful treatment options for cancer result in more young long-term survivors prone for long-term complications. Carotid artery vasculopathy is a potential long-term complication after radiotherapy of the n...

    Authors: Joyce Wilbers, Arnoud C Kappelle, Roy PC Kessels, Stefan CA Steens, Frederick JA Meijer, Johannes H Kaanders, Roy AM Haast, Laura E Versteeg, Anil M Tuladhar, Chris L de Korte, Hendrik HG Hansen, Frank J Hoebers, Willem Boogerd, Erik D van Werkhoven, Marlies E Nowee, Guus Hart…
    Citation: BMC Neurology 2014 14:132
    Content type: Study protocol Published on:

  48. Temporal lobe epilepsy (TLE) and idiopathic generalized epilepsy (IGE) patients have each been associated with extensive brain atrophy findings, yet to date there are no reports of head to head comparison of b...

    Authors: Hila Goldberg, Arie Weinstock, Niels Bergsland, Michael G Dwyer, Osman Farooq, Mona Sazgar, Guy Poloni, Cierra Treu, Bianca Weinstock-Guttman, Murali Ramanathan and Robert Zivadinov
    Citation: BMC Neurology 2014 14:131
    Content type: Research article Published on:

  49. Escherichia coli (E. coli) is the most common causative bacteria of neonatal meningitis, but hematogenous intracranial E. coli infection is rare in adults. Moreover, intracranial abscess formation owing to E. co...

    Authors: Nobuhiro Akuzawa, Tenshi Osawa, Masayuki Totsuka, Takashi Hatori, Kunihiko Imai, Yonosuke Kitahara and Masahiko Kurabayashi
    Citation: BMC Neurology 2014 14:130
    Content type: Case report Published on:

  50. Responsiveness of a measurement tool is its ability to detect change over time. The aim of this study was to determine the responsiveness and floor/ceiling effects of the ten-metre walk test (10mWT), Step Test...

    Authors: Katharine Scrivener, Karl Schurr and Catherine Sherrington
    Citation: BMC Neurology 2014 14:129
    Content type: Research article Published on:
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BMC Neurology

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