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  1. Since the beginning of the COVID-19 pandemic and development of new vaccines, the issue of post-vaccination exacerbation or manifestation of demyelinating central nervous system (CNS) disorders has gained incr...

    Authors: Lisa Lohmann, Felix Glaser, Gabriel Möddel, Jan D. Lünemann, Heinz Wiendl and Luisa Klotz
    Citation: BMC Neurology 2022 22:185
  2. It is critical for stroke survivors in working age to develop skills and confidence for long-term self-management of physical activity and exercise training to maintain a healthy lifestyle and decrease the ris...

    Authors: Kirsti S. Roaldsen, Charlotte Walter, Johan Gäverth and Ing-Mari Dohrn
    Citation: BMC Neurology 2022 22:183
  3. Congenital absence of the internal carotid artery (ICA) is a highly infrequent congenital incidence and occurs in less than 0.01% of the population; bilateral absence is exceedingly rare, diagnosed below 10% o...

    Authors: Ivana Markovic, Zoran Milenkovic, Bosanka Jocic-Jakubi, Amna Al Futaisi, Kakaria Anupam Kakaria and Yasser Walli
    Citation: BMC Neurology 2022 22:182
  4. Bromine compounds are used in several drugs, including over-the-counter drugs. They sometimes cause intoxication known as bromism. Although the acute neurological symptoms and sequelae of bromism vary, few rep...

    Authors: Masahiro Biyajima, Shunichi Satoh, Takahiro Morikawa, Yuki Morita, Rie Watanabe, Daisuke Matsui, Masataka Konno, Nobutoshi Morimoto, Yuichi Yatsu, Akihito Hirasaki and Hiroyuki Yahikozawa
    Citation: BMC Neurology 2022 22:181
  5. Hereditary spastic paraplegia (HSP) is a group of neurodegenerative diseases characterized by lower-limb spastic paraplegia with highly genetic and clinical heterogeneity. However, the clinical sign of spastic...

    Authors: Jiannan Chen, Zhe Zhao, Hongrui Shen, Qi Bing, Nan Li, Xuan Guo and Jing Hu
    Citation: BMC Neurology 2022 22:180
  6. Disruption of brain functional connectivity has been detected after stroke, but whether it also occurs in moyamoya disease (MMD) is unknown. Impaired functional connectivity is always correlated with abnormal ...

    Authors: Junwen Hu, Yin Li, Zhaoqing Li, Jingyin Chen, Yang Cao, Duo Xu, Leilei Zheng, Ruiliang Bai and Lin Wang
    Citation: BMC Neurology 2022 22:179
  7. Wilson’s disease is a hereditary disorder of copper metabolism resulting mainly in hepatic, neurological, and psychiatric symptoms. Multiple sclerosis (MS) is an immune-mediated demyelinating disease affecting...

    Authors: Katalin Despotov, Péter Klivényi, István Nagy, Attila Pálvölgyi, László Vécsei and Cecília Rajda
    Citation: BMC Neurology 2022 22:178
  8. Regular physical activity is of great relevance in Parkinson's disease (PD). It is part of the inpatient multimodal Parkinson's complex treatment (MKP) in Germany. However, there is often a lack of human resou...

    Authors: Lynn Wagner, Björn Hauptmann, Ann-Kristin Hoffmann, Nicole Jochems, Bastian Schmeier, Andreas Schrader, Thomas Kohlmann and Ruth Deck
    Citation: BMC Neurology 2022 22:176
  9. Many stroke survivors have multiple chronic diseases and complications coupled with various other factors which may affect their functional status. We aimed to investigate the factors associated with poor func...

    Authors: Jing Zhou, Fang Liu, Mingchao Zhou, Jianjun Long, Fubing Zha, Miaoling Chen, Jiehui Li, Qingqing Yang, Zeyu Zhang and Yulong Wang
    Citation: BMC Neurology 2022 22:173
  10. Authors: Derek L. Isenberg, Kevin A. Henry, Adam Sigal, Traci Deaner, Jason T. Nomura, Kathleen A. Murphy, Derek Cooney, Susan Wojcik, Ethan S. Brandler, Alexander Kuc, Gerard Carroll, Chadd K. Kraus, Judy B. Shahan, Joseph Herres, Daniel Ackerman and Nina T. Gentile
    Citation: BMC Neurology 2022 22:171

    The original article was published in BMC Neurology 2022 22:132

  11. Aquatic physiotherapy is becoming a more frequently utilised treatment for people with Parkinson’s Disease (PD). Consumers are increasingly accessing information regarding health choices online, and it is not ...

    Authors: Aan Fleur Terrens, Sze-Ee Soh and Prue Morgan
    Citation: BMC Neurology 2022 22:170
  12. Bupropion, an antidepressant inhibiting the reuptake of dopamine and noradrenaline, should be useful to treat depressive symptoms in patients with Parkinson’s disease (PD). Limited and conflicting literature d...

    Authors: Matteo Vismara, Beatrice Benatti, Gregorio Nicolini, Ilaria Cova, Edoardo Monfrini, Alessio Di Fonzo, Vincenza Fetoni, Caterina A. Viganò, Alberto Priori and Bernardo Dell’Osso
    Citation: BMC Neurology 2022 22:169
  13. HINT1 mutations cause an autosomal recessive axonal neuropathy with neuromyotonia. This is a first case report of coexistence of myasthenia gravis (MG) and HINT1-related motor axonal neuropathy without neuromyoto...

    Authors: Jia Fang, Hui Huang, Qiang Lei, Yingying Luo, Zhengchu Tang, Xiaoliu Shi and Jian Guang Tang
    Citation: BMC Neurology 2022 22:168
  14. Lysophosphatidic acid (LPA) is a common glycerol phospholipid and an important extracellular signaling molecule. LPA binds to its receptors and mediates a variety of biological effects, including the pathophys...

    Authors: Yaya Wang, Jie Zhang, Liqin Huang, Yanhong Mo, Changyu Wang, Yiyi Li, Yangyang Zhang and Zhaohui Zhang
    Citation: BMC Neurology 2022 22:166
  15. As a debilitating syndrome, paraneoplastic cerebellar degeneration (PCD) remains challenging to treat. Further, anti-Yo antibody (directed against human cerebellar degeneration-related protein 2) detection in ...

    Authors: Takeshi Imai, Kensuke Shinohara, Kenji Uchino, Hirohisa Okuma, Futaba Maki, Kiyoshi Hiruma, Yasushi Ariizumi and Yoshihisa Yamano
    Citation: BMC Neurology 2022 22:165
  16. Idiopathic intracranial hypertension is a rare neurological condition among children. Its manifestations vary from mild headaches to loss of vision. Although rare, COVID-19 infection and high dose cytosine ara...

    Authors: Rim Rakez, Wiem Boufrikha, Sana Lakhal, Amel Boughammoura and Mohamed Adnene Laatiri
    Citation: BMC Neurology 2022 22:163
  17. Duchenne muscular dystrophy (DMD) is the most common muscular dystrophy in the pediatric population. The manifestations of this disease include progressive muscle weakness, gait dysfunction, and motor impairme...

    Authors: Gholamreza Zamani, Sareh Hosseinpour, Mahmoud Reza Ashrafi, Mahmoud Mohammadi, Reza Shervin Badv, Ali Reza Tavasoli, Masood Ghahvechi Akbari, Ali Hosseini Bereshneh, Reza Azizi Malamiri and Morteza Heidari
    Citation: BMC Neurology 2022 22:162
  18. Palliative sedation has become widely accepted as a method to alleviate refractory symptoms in terminally ill patients. Controversies regarding this topic especially concern the use of palliative sedation for ...

    Authors: Laura Salzmann, Bernd Alt-Epping and Alfred Simon
    Citation: BMC Neurology 2022 22:161
  19. Operating an aircraft is associated with a large mental workload; however, knowledge of the mental workload of ROV operators is limited. The purpose of this study was to establish a digital system for assessin...

    Authors: Liya Tang, Juanning Si, Lei Sun, Gengsheng Mao and Shengyuan Yu
    Citation: BMC Neurology 2022 22:160
  20. The KHENERGYC trial will be a phase II, randomised, double-blinded, placebo-controlled (DBPC), parallel-group study in the paediatric population (birth up to and including 17 years). The study will be recruiti...

    Authors: Jan Smeitink, Rob van Maanen, Lonneke de Boer, Gerrit Ruiterkamp and Herma Renkema
    Citation: BMC Neurology 2022 22:158
  21. We assess the impact of prevention strategies regarding type 2 diabetes as a modifiable risk factor for dementia and its consequences for the future number of dementia patients in Germany.

    Authors: Anne Fink, Achim Doerre, Ilja Demuth and Gabriele Doblhammer
    Citation: BMC Neurology 2022 22:157
  22. Hemorrhagic transformation (HT) is the most alarming complication of acute ischemic stroke. We aimed to identify risk factors for HT in Chinese patients and attempted to develop a nomogram to predict individua...

    Authors: Keming Zhang, Jianfang Luan, Changqing Li and Mingli Chen
    Citation: BMC Neurology 2022 22:156
  23. It is common for people with persistent spasticity due to a stroke to receive an injection of botulinum toxin-A in the upper limb, however post-injection intervention varies.

    Authors: Natasha A. Lannin, Louise Ada, Coralie English, Julie Ratcliffe, Steven Faux, Mithu Palit, Senen Gonzalez, John Olver, Emma Schneider, Maria Crotty and Ian D. Cameron
    Citation: BMC Neurology 2022 22:154
  24. Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most frequent autoimmune paraneoplastic encephalitis, and is primarily associated with ovarian teratomas. Here, we report the first case of a pati...

    Authors: Ying Yu, Jun-Li Liu and Dai-Shi Tian
    Citation: BMC Neurology 2022 22:153
  25. The Guillain-Barre Syndrome (GBS), also known as acute idiopathic polyneuritis, is a critical acquired condition associated with preceding nonspecific infection or triggering factors like trauma, surgery, or v...

    Authors: Priyank Patel, Darshil Shah, Chinmay Jani, Jui Shah, Ruchi Jani, Arjun Kelaiya, Jinal Pandya, Harpreet Singh, Omar Al Omari, Dhara Roy, Irmgard Behlau and Ami Parikh
    Citation: BMC Neurology 2022 22:151
  26. Neuronal intranuclear inclusion disease (NIID) is a rare neurodegenerative disease characterized by eosinophilic hyaline intranuclear inclusions in cells in the central and peripheral nervous system. High-inte...

    Authors: Hongfen Wang, Feng Feng, Jiajin Liu, Jianwen Deng, Jiongming Bai, Wei Zhang, Luning Wang, Baixuan Xu and Xusheng Huang
    Citation: BMC Neurology 2022 22:150
  27. We do not yet know whether or the extent to which multimodal therapy changes the health behaviors and health service use of chronic headache patients in the long term. Associations are expected between pain sy...

    Authors: Carolin Donath, Katharina Luttenberger, Christa Geiß, Patricia Albert and Britta Fraunberger
    Citation: BMC Neurology 2022 22:149
  28. A variety of management options (e.g., disease-modifying therapy, lifestyle interventions, rehabilitation) are available for persons with relapsing-remitting multiple sclerosis (MS). Besides coping with the di...

    Authors: Anna Sippel, Jutta Scheiderbauer, Désirée Eklund, Sigrid Arnade, Stephan Schmidt, Ingo Kleiter, Rebecca Morrison, Christopher Kofahl and Christoph Heesen
    Citation: BMC Neurology 2022 22:146
  29. The use of patient reported outcomes measures (PROMs) may offer utility that are important for stroke survivors. This study assessed the PROMIS-10, which contains Mental health (MH) and Physical Health (PH) do...

    Authors: Amber E. Corrigan, Ben Carter, Alexander Smith, Anna Pennington and Jonathan Hewitt
    Citation: BMC Neurology 2022 22:145
  30. As a chronic, disabling disease, multiple sclerosis (MS) has challenged healthcare systems in many ways. MS adversely affects patients’ quality of life and self-efficacy and results in psychological stress. Th...

    Authors: Mostafa Bijani, Maryam Niknam, Shanaz Karimi, Zeinab Naderi and Azizallah Dehghan
    Citation: BMC Neurology 2022 22:144
  31. Fingolimod, an oral sphingosine 1-phosphate receptor immunomodulator, is approved in Europe for people with multiple sclerosis (pwMS) with highly active disease despite a full and adequate course of treatment ...

    Authors: Veronika Tichá, Zuzana Počíková, Josef Vytlačil and Radka Štěpánová
    Citation: BMC Neurology 2022 22:143
  32. Hyperintense Acute Reperfusion Marker (HARM) is a hyperintense subarachnoid signal on FLAIR MRI sequence caused by gadolinium contrast leakage into the subpial space. While, on FLAIR, HARM may mimic subarachno...

    Authors: Luigi Francesco Saccaro, Imen Bekri, Maxime De Malherbe, Intissar Hmida and Fernando Pico
    Citation: BMC Neurology 2022 22:142
  33. We previously characterized hemisphere-specific motor control deficits in the ipsilesional, less-impaired arm of unilaterally lesioned stroke survivors. Our preliminary data indicate these deficits are substan...

    Authors: Candice Maenza, Robert L. Sainburg, Rini Varghese, Brooke Dexheimer, Marika Demers, Lauri Bishop, Shanie A. L. Jayasinghe, David A. Wagstaff and Carolee Winstein
    Citation: BMC Neurology 2022 22:141
  34. People with amyotrophic lateral sclerosis (ALS) are at high risk for severe outcomes from Covid-19 infection. Researchers exploring ALS and Covid-19 have focused primarily on system response and adaptation. Us...

    Authors: Shelagh K. Genuis, Westerly Luth, Tania Bubela and Wendy S. Johnston
    Citation: BMC Neurology 2022 22:140
  35. Glioblastoma multiforme (GBM) is the most common aggressive malignant brain tumor. However, the molecular mechanism of glioblastoma formation is still poorly understood. To identify candidate genes that may be...

    Authors: Jianmin Li, Zhao Zhang, Ke Guo, Shuhua Wu, Chong Guo, Xinfan Zhang and Zi Wang
    Citation: BMC Neurology 2022 22:139
  36. Meningiomas and unruptured cerebral aneurysms (UCAs) rarely coexist. However, the treatment strategy remains to be fully elucidated. This report is a first report that UCA related to the tumor feeder intraoper...

    Authors: Shingo Tanaka, Masaaki Kobayashi, Toshiya Ichinose, Nozomu Oikawa, Masashi Kinoshita, Akifumi Yoshikawa, Naoyuki Uchiyama and Mitsutoshi Nakada
    Citation: BMC Neurology 2022 22:135
  37. We report a rare case of Godtfredsen syndrome caused by clival chondrosarcoma and perform a review of literatures. This article also explains the clinico-anatomical correlation of this rare neurological syndrome.

    Authors: Yong Zheng Wai, Yong Yuin Chong, Noraini Mohd Dusa, Yin Peng Lai and Lik Thai Lim
    Citation: BMC Neurology 2022 22:134

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