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Table 1 Demographic and baseline characteristics

From: Perfusion deficits in thrombolysis-treated acute ischemic stroke patients with negative or positive diffusion-weighted imaging

Characteristics

DWI-negative (n = 35)

DWI-positive (n = 116)

P value

Age, years, mean ± SD

64.7 ± 8.8

64.8 ± 12.2

0.971

Sex, males, n (%)

22.0(62.9)

80.0(69.0)

0.499

NIHSS score before IVT

3.0(1.5-4.0)

4.0(2.0–8.0)

0.100

NIHSS score after IVT

1.0(0–2.0)

2.0(0–5.0)

0.045

Vessel stenosis or occlusion, n (%)

9(25.7)

43(37.1)

0.215

DNT, minute

57.0(51.0–66.0)

59.0(50.0–70.0)

0.793

HT, n (%)

26.0(74.3)

74.0 (63.8)

0.250

DM, n (%)

13.0 (37.1)

41.0 (35.3)

0.846

CHD, n (%)

8.0 (22.9)

20.0 (17.2)

0.454

AF, n (%)

0(0.0)

14.0 (12.1)

0.021

Hyperlipidemia, n (%)

16.0 (45.7)

45.0 (38.8)

0.465

CI history, n (%)

6.0 (17.1)

16.0 (13.8)

0.622

Smoking, n (%)

19.0 (54.3)

58.0 (50.0)

0.657

Drinking, n (%)

11.0 (31.4)

39.0 (33.6)

0.809

SBP, mmHg

154.0 (135.5-164.5)

154.0 (139.5–163.0)

0.650

DBP, mmHg

82.0(77.0–90.0)

82.5(75.5–94.0)

0.610

BMI

24.8(23.4–26.8)

25.0(23.0-27.7)

0.985

Blood glucose level, mmol/l

7.8(6.8–9.8)

7.0(5.7–9.9)

0.829

TC, mmol/L

4.8 ± 1.1

4.7 ± 1.1

0.949

TG, mmol/L

2.2(1.8–3.2)

3.1(2.4–3.9)

0.018

HDL-C, mmol/L

1.1(1.0-1.2)

1.1(0.9–1.2)

0.334

LDL-C, mmol/L

3.0 ± 1.1

3.1 ± 1.0

0.763

Lipoprotein (a), mg/dL

16.3(9.2–20.3)

19.1(9.8–38.5)

0.341

Cr, umol/L

73.8 ± 15.4

68.7 ± 15.6

0.092

HbA1c, %

6.4(5.8-7.0)

6.0(5.7–7.2)

0.863

Hcy, umol/L

12.0(10.0–15.0)

12.0(11.0–16.0)

0.315

Uric acid, umol/L

344.0 ± 102.0

337.7 ± 95.5

0.739

Duration of admission in days

9.0(8.0–10.0)

10.5(9.0–12.0)

< 0.001

mRS at discharge

0(0–1.0)

2.0(1.0–3.0)

< 0.001

Poor function outcome

1(2.9)

37(31.9)

< 0.001

  1. Abbreviations: DWI diffusion weighting imaging, SD standard deviation, NIHSS National Institutes of Health Stroke Scale, IVT Intravenous thrombolysis, DNT door to needle time, HT hypertension, DM diabetes, CHD coronary heart disease, AF atrial fibrillation, CI cerebral infarction, SBP systolic blood pressure, DBP diastolic pressure, BMI body mass index, TC total cholesterol, TG triglyceride, Cr creatinine, Hcy homocysteine, mRS modified Rankin scale