Increasing C-reactive protein levels in a patient with glioblastoma with lymph node metastasis: a case report

Kanemitsu, Takuya; Furuse, Motomasa; Kuwabara, Hiroko; Yagi, Ryokichi; Hiramatsu, Ryo; Kameda, Masahiro; Nonoguchi, Naosuke; Kawabata, Shinji; Takami, Toshihiro; Arai, Motohiro; Wanibuchi, Masahiko

doi:10.1186/s12883-023-03402-4

BMC Neurology

Table 1 Summary of reported glioblastoma cases with lymph node metastasis

From: Increasing C-reactive protein levels in a patient with glioblastoma with lymph node metastasis: a case report

Author	Age	Sex	Lymph node metastasis	The other metastasis	Intracranial tumor	Symptom	Duration from initial Dx	Treatment	Survival time (months)
Nigogosyan [12], 1962	40	M	Mediastinal	Lung, vertebrae, sternum	Local progression	None (autopsy)	7.5	None	N/A
Komatsu [13], 1972	18	F	Cervical	Scalp	Local progression	Lymphadenopathy	7	Surgery, radiotherapy	2
Hulbanni [14], 1976	63	M	Bronchial	Lung, vertebrae	Local progression	None (autopsy)	0	None	0
Pasquier [15], 1980	21	F	Submandibular	Liver	Local progression	Lymphadenopathy	0.5	Surgery	1
Steinbok [16], 1985	27	F	Submental and cervical	None	Local progression	Lymphadenopathy	45	Surgery, radiotherapy, chemotherapy	17
Trattnig [17], 1990	29	M	Cervical	Bones	Local progression	Retromandibular swelling	18	Surgery, radiotherapy, chemotherapy	14
Zappia [18], 1992	39	M	Submandibular and deep cervical, parotid chains	None	Local progression	Lymphadenopathy	19	Chemotherapy	N/A
Wallase [19], 1996	41	M	Cervical and supraclavicular	Extraocular muscle	None	Painful lymphadenopathy	3	Radiotherapy, chemotherapy	5
Wallase [19], 1996	37	M	Auricular	Orbit	Local progression	Headache, drowsiness, facial numbness	5	Second craniotomy	2
al-Rikabi [20], 1997	4	M	Cervical	None	N/A	Lymphadenopathy, fever	1	N/A	N/A
Montagne [21], 2004	74	F	Mediastinal	Lung, vertebrae	Local progression	Thrombocytopenia, diffuse myelalgia	0	N/A	2
Moon [22], 2004	35	F	Cervical	Scalp	Local progression	Lymphadenopathy, headache, nausea	48	Chemotherapy	4
Taha [23], 2005	33	M	Cervical, parotid gland	None	Local progression	Lymphadenopathy	5.5	Radiotherapy, chemotherapy	3
Didelot [24], 2006	74	M	Mediastinal	Bone marrow, lung	None	Pancytopenia	0	Chemotherapy	2
Piccirilli [10], 2007	70	F	Cervical	None	Local progression	Lymphadenopathy	20	N/A	10
Mujtaba[25], 2013	20	M	Supraclavicular	None	N/A	Lymphadenopathy , cough	19	Surgery, radiotherapy, chemotherapy	N/A
Blume [5], 2013	35	M	Pulmonary	Lung, vertebrae	None	Tetraparesis	N/A	Surgery, radiotherapy, chemotherapy	10
Xu [26], 2016	58	F	Cervical	Bones	None	Lymphadenopathy	29	Surgery, radiotherapy, chemotherapy	25
Kanemitsu, 2023	48	M	Supraclavicular and mediastinal	Lung	None	Fever, CRP increasing	34	Radiotherapy, chemotherapy	4

F: Female, M: male, N/A: not available

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