| | Univariable | | Multivariable |
|---|
| | Exp(B) | p | Exp(B) | 95% CI | p |
|---|
Age | 1.035 | 0.078 | 1.043 | 0.993–1.097 | 0.095 |
Sex (F) | 2.586 | 0.056 | 1.079 | 0.283–4.111 | 0.915 |
Onset-to-sample time | 8.217 | < 0.001*** | 9.141 | 2.113–39.549 | 0.003** |
Recurrent disease | 0.714 | 0.674 | – | – | – |
Lesion length | 1.642 | 0.001** | 1.848 | 1.249–2.734 | 0.002** |
lnNLR | 6.805 | < 0.001*** | 4.266 | 1.220–14.912 | 0.023* |
- Worst EDSS was dichotomized as moderate to severe disability (EDSS ≥ 4) or mild (EDSS less than 4). Worst EDSS was the EDSS assessed at nadir (in monophasic patients), or at recur or at last follow-up (in recurrent patients). Variables included in the multivariable model (age, sex, onset-to-sample time, MRI lesion length, lnNLR) were selected from significant variables in the univariable analysis as well as adjusted variables. Nagelkerke pseudo R-squared value of the final multivariable model was 0.498
- EDSS expanded disability status scale, CI confidence interval, F female sex (compared to male), lnNLR natural log-transformed neutrophil-to-lymphocyte ratio
- *p < 0.05; **p < 0.01, ***p < 0.001
