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Table 3 Multilevel logistic regression analysis of factors associated with Neurolathyrism in Dawunt wereda, North Wollo zone, Northeastern Ethiopia; 2021

From: Prevalence of Neurolathyrism and its associated factors in Grass pea cultivation areas of Dawunt District, North-eastern Ethiopia; 2022: a community based multilevel analysis

Variables

Neurolathyrism

Model-1

Model-2

AOR

(95% CI)

Model-3

AOR

(95% CI)

Model-4

AOR

(95% CI)

P-value

(model-4)

Yes

No

Random effects

ICC (95% CI)

  

0.573

(0.435, 0.701)

0.593

(0.431, 0.738)

0.414

(0.269, 0.576)

0.384

(0.227, 0.569)

 

PCV

  

Reference

-8.5%

47.4%

53.6%

 

Variance (SE)

  

4.42

(1.26)

4.80

(1.61)

2.33

(0.77)

2.05

(0.79)

 

MOR

  

11.49

12.74

5.89

5.27

 

Model fitness

AIC

  

709.218

653.065

607.089

538.545

 

BIC

  

721.451

726.466

698.839

679.229

 

Log likelihood

  

-352.609

-314.533

-288.544

-246.272

 

Individual level variables

Age group

1-17years

11

1397

 

1

 

1

 

18-64years

69

1828

 

5.39*

(1.93, 15.04)

 

7.38***

(2.64, 20.61)

< 0.001

65+years

1

44

 

1.16

(0.08, 17.14)

 

1.42

(0.11, 19.02)

0.792

Sex

Male

66

1554

 

6.54*

(3.32, 12.89)

 

7.76***

(3.91, 15.40)

< 0.001

Female

15

1715

 

1

 

1

 

Educational status

No formal education

41

1320

 

2.95*

(0.91, 9.59)

 

3.18

(0.99, 10.23)

0.052

Primary

25

1282

 

2.02*

(0.78, 5.29)

 

2.39

(0.93, 6.18)

0.071

Secondary+

15

667

 

1

 

1

 

Marital status

Married

40

1201

 

1

 

1

 

Divorced

3

35

 

4.76*

(0.80, 28.28)

 

2.05

(0.29, 14.13)

0.468

Widowed

1

32

 

1.74

(0.15, 20.38)

 

0.80

(0.08, 8.59)

0.856

Not ever marriedX

37

2001

 

2.99*

(0.92, 9.68)

 

4.02**

(1.26, 12.81)

0.018

Occupation

Farmer

44

1151

 

1.77

(0.52, 6.02)

 

2.00

(0.63, 6.34)

0.238

Not occupiedY

3

432

 

0.32*

(0.06, 1.83)

 

0.27

(0.05, 1.54

0.140

Non-farmerZ

34

1686

 

1

 

1

 

Household level variables

Family size

< 5

24

673

  

11.96*

(2.93, 48.75)

12.64***

(3.02, 52.81)

0.001

5–7

51

2065

  

3.75*

(1.04, 13.49)

3.27

(0.90, 11.85)

0.072

> 7

6

531

  

1

1

 

Average monthly income

< 1000 ETB

71

2692

  

3.43*

(0.58, 20.30)

3.57

(0.59, 21.66)

0.166

1000–2000 ETB

8

347

  

2.69

(0.37, 19.40)

2.75

(0.37, 20.24)

0.320

> 2000 ETB

2

230

  

1

1

 

Main income source

Farming

80

3161

  

3.18

(0.13, 78.75)

  

Non-farming

1

108

  

1

  

Farming land

Yes

80

3225

  

0.51

(0.02, 17.17)

  

No

1

44

  

1

  

Annual grass pea production

< 6quintals

36

2370

  

1

1

 

6 quintals+

45

899

  

4.66*

(2.14, 10.14)

4.99***

(2.26, 10.99)

< 0.001

Family ever feed grass pea only

Yes

30

210

  

8.32*

(3.29, 21.02)

8.75***

(3.45, 22.21)

< 0.001

No

51

3059

  

1

1

 

Main cooking utensils

Clay materials

72

2685

  

1.88*

(0.67, 5.27)

2.04

(0.70, 5.91)

0.190

Non-clay materials

9

584

  

1

1

 

Grass pea to other cereals mixing ratio

< 1:1

63

3104

  

1

1

 

1:1 to 3:1

12

132

  

3.32*

(1.03, 10.70)

3.78**

(1.16, 12.28)

0.027

> 3:1

6

33

  

5.48*

(0.91, 33.02)

6.05**

(1.09, 33.47)

0.039

Ever feeding roasted grass pea

Yes

23

391

  

2.01*

(0.81, 4.99)

2.10

(0.85, 5.16)

0.107

No

58

2878

  

1

1

 

Ever feeding immature seeds

Yes

47

506

  

5.38*

(2.42, 11.97)

6.28***

(2.80, 14.08)

< 0.001

No

34

2810

  

1

1

 
  1. XIncludes singles and the non-eligible (Male < 20 years; Female less than 18 years)
  2. YIncludes non-occupied (if age ≥ 7years) and the non-eligible (Age < 7years)
  3. ZIncludes merchants, government employs, private employs, and students
  4. *Significant at p-value < 0.25 in Model-2 or Model-3
  5. **Statistically significant at p-value < 0.05 in the final model (Model-4)
  6. ***Statistically significant at p-value ≤ 0.001 in the final model (Model-4)
  7. AIC, Akaike Information Criteria; AOR, Adjusted Odds Ratio; BIC, Bayesian Information Criteria; CI, Confidence Interval; ICC, Intra-cluster Correlation Coefficient; MOR, Median Odds Ratio; PCV, Proportional Change in Variance; SE, Standard Error