Comparisons of clinical characteristics, brain MRI findings, and responses to epidural blood patch between spontaneous intracranial hypotension and post-dural puncture headache: retrospective study

Table 1 Demographics, clinical features, and EBP response rate in SIH and PDPH patients

Variables	SIH (n = 61)	PDPH (n = 44)	p-value
Age (years)	40 (33–51)	38 (29.5–53)	0.471
Gender			0.615
Male	24 (39.3%)	21 (47.7%)
Female	37 (40.7%)	23 (52.3%)
Symptom onset-diagnosis interval (days)	10 (6–15)	4 (3–10.5)	< 0.01
Time to occur a headache after sitting (minutes)	5 (1–10)	8 (4–10)	0.518
Headache intensity (0–10)	7 (5–9)	7 (6–8)	0.651
Associated phenomena
Nausea	32 (52.5%)	19 (43.2%)	0.317
Vomiting	15 (24.6%)	6 (13.6%)	0.240
Auditory symptoms	12 (19.7%)	3 (6.8%)	0.060
Dizziness	5 (8.2%)	3 (6.8%)	0.661
CSF opening pressure (cmH₂O)	5.5 (3–8) (n = 40)	6.5 (4–9) (n = 22)	0.188
Hospitalization period (days)	7 (5–9.25)	6 (4–8.5)	0.087
Treatment			0.015
Conservative management	18 (29.5%)	24 (54.5%)
EBP once	20 (32.8%)	14 (31.8%)
EBP twice	17 (27.9%)	2 (4.5%)
EBP three times	3 (4.9%)	4 (9%)
EBP four times	3 (4.9%)	0 (0%)

spontaneous intracranial hypotension (SIH); post-dural puncture headache (PDPH); cerebrospinal fluid (CSF); epidural blood patch (EBP)
Values are presented as the number of patients (%) or median (IQR)

ISSN: 1471-2377