Increase of blood-brain barrier leakage is related to cognitive decline in vascular mild cognitive impairment

BMC Neurology

Table 2 Cognitive function in different domains of participants

	vMCI group N = 26	Control N = 21	P
Overall cognitive function
MMSE	26.31 ± 1.12	29.24 ± 0.70	<0.001
MoCA	23.04 ± 2.32	28.00 ± 1.22	<0.001
Memory
Delayed recall	4.62 ± 0.50	4.86 ± 0.36	0.059
DST-forward	7.85 ± 0.78	8.33 ± 0.97	0.063
DST-backward	3.77 ± 0.65	4.10 ± 0.70	0.106
Information processing speed
TMT-A	59.23 ± 10.88	39.81 ± 9.11	<0.001
Attention
SDMT	31.81 ± 4.45	39.57 ± 6.52	<0.001
Executive function
TMT B-A	85.96 ± 31.97	56.71 ± 19.54	0.001
SCWT C-B	68.31 ± 24.81	49.81 ± 21.02	0.009
Spatial function
Clock Drawing Test	3.31 ± 0.55	3.81 ± 0.40	0.001
Language function
VFT	42.38 ± 10.09	51.43 ± 7.21	0.001

Data are presented as mean ± SD, or counts (%)
Abbreviations: N number of persons, vMCI mild vascular cognitive impairment, MMSE Mini-Mental State Examination, MoCA Montreal Cognitive Assessment, DST digit span test, SDMT symbol digital modalities test, SCWT stroop color word test, CDT clock drawing test, VFT verbal fluency test

ISSN: 1471-2377