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Table 1 Demographic and clinical features between PD patients with and without FT

From: Facial tremor in patients with Parkinson’s disease: prevalence, determinants and impacts on disease progression

 

Total

(n = 2224)

With FT

(n = 403)

Without FT

(n = 1821)

P-value

Education

9.5 ± 4.1

9.0 ± 4.3

9.6 ± 4.0

0.016*

Sex, male

1181 (53.1%)

171 (42.4%)

1010 (55.5%)

< 0.001*

Age

62.3 ± 9.9

65.4 ± 9.7

61.6 ± 9.9

< 0.001*

Age at onset

58.9 ± 9.9

60.8 ± 10.1

58.5 ± 9.9

< 0.001*

Disease duration

3.4 ± 3.4

4.5 ± 4.2

3.1 ± 3.1

< 0.001*

LEDD

232.0 ± 275.7

241.6 ± 310.0

229.9 ± 267.6

0.485

UPDRS-IIIa

29.2 ± 14.2

32.5 ± 17.4

28.4 ± 13.3

< 0.001*

Speech

0.7 ± 0.7

0.8 ± 0.8

0.7 ± 0.7

< 0.001*

Facial expression

1.5 ± 0.8

1.5 ± 0.9

1.5 ± 0.8

0.215

Tremor at resta

2.2 ± 2.4

3.3 ± 2.9

1.9 ± 2.1

< 0.001*

Action or postural tremor

1.6 ± 1.4

2.2 ± 1.9

1.4 ± 1.3

< 0.001*

Rigidity

8.0 ± 3.9

8.1 ± 4.4

8.0 ± 3.8

0.607

Bradykinesia

12.3 ± 6.8

13.2 ± 7.7

12.0 ± 6.6

< 0.001*

Axial symptoms

3.0 ± 2.7

3.3 ± 3.1

2.9 ± 2.5

0.006*

H&Y stage

2.0 (0.5)

2.0 (0.5)

2.0 (0.5)

0.025*

Freezing of gait

462 (20.8%)

95 (23.6%)

367 (20.2%)

0.126

Falls

151 (6.8%)

32 (7.9%)

119 (6.5%)

0.310

Motor fluctuation

212 (9.5%)

88 (14.7%)

340 (12.2%)

0.087

Dyskinesia

76 (3.4%)

33 (5.5%)

169 (6.0%)

0.623

FAB

15.2 ± 2.7

14.8 ± 2.8

15.3 ± 2.7

0.001*

MoCA

22.9 ± 4.8

22.0 ± 5.1

23.1 ± 4.7

< 0.001*

HDRS

9.4 ± 8.2

9.8 ± 8.1

9.3 ± 8.2

0.244

Depression

727 (32.7%)

145 (36.0%)

582 (32.0%)

0.120

HARS

7.2 ± 6.6

7.3 ± 6.7

7.1 ± 6.6

0.631

Anxiety

653 (29.4%)

128 (33.8%)

525 (30.8%)

0.242

NMSS

35.7 ± 30.5

39.0 ± 32.9

34.9 ± 29.9

0.024*

  1. PD Parkinson’s disease, FT Facial tremor, LEDD Levodopa Equivalent Daily Doses, UPDRS Unified PD Rating Scale, H&Y stage Hoehn and Yahr stage, FAB Frontal Assessment Battery, MoCA Montreal Cognitive Assessment, HDRS Hamilton Depression Rating Scale, HARS Hamilton Anxiety Rating Scale, NMSS Non-Motor Symptoms Scale
  2. aThe total score was calculated after excluding the score of FT at rest
  3. * Significant difference