From: Stroke etiologies in patients with COVID-19: the SVIN COVID-19 multinational registry
All patients acute ischemic strokea (n = 156) | Cryptogenic stroke (n = 55) | Cardioembolic stroke (n = 35) | Large vessel stroke (n = 15) | Small vessel stroke (n = 4) | Other (n = 11) | p-valueb | p-valuec | |
---|---|---|---|---|---|---|---|---|
Hemorrhagic transformation of infarction, no. (%) | 17/98 (17.4) | 6/42 (14.3) | 3/26 (11.5) | 0/8 (0) | 0/4 (0) | 4/7 (57.1) | 0.05 | 0.55 |
Grade of hemorrhage | > 0.9 | 0.82 | ||||||
HI-1 | 7/17 (41.2) | 3/6 (50.0) | 1/3 (33.3) | n/a | n/a | 2/4 (50.0) | ||
HI-2 | 2/17 (11.8) | 1/6 (16.7) | 0/3 (0) | n/a | n/a | 1/4 (25.0) | ||
PH-1 | 4/17 (23.5) | 1/6 (16.7) | 1/3 (33.3) | n/a | n/a | 1/4 (25.0) | ||
PH-2 | 4/17 (23.5) | 1/6 (16.7) | 1/3 (33.3) | n/a | n/a | 0/4 (0) | ||
Symptomatic ICHd, no. (%) | 1/14 (7.1) | 1/4 (25.0) | 0/3 (0) | n/a | n/a | 0/4 (0) | > 0.9 | > 0.9 |
Transfer to ICU, no. (%) | 69/145 (47.6) | 26/52 (50.0) | 11/33 (33.3) | 10/15 (66.7) | 0/4 (0) | 10/11 (90.9) | < 0.01 | 0.36 |
Intubation, no. (%) | 51/139 (36.7) | 17/47 (36.2) | 7/32 (21.9) | 4/15 (26.7) | 0/4 (0) | 7/11 (63.6) | 0.08 | 0.56 |
Discharge disposition, no. (%) | 0.57 | 0.55 | ||||||
Home | 34/136 (25.0) | 11/50 (22.0) | 9/29 (31.0) | 4/14 (28.6) | 2/4 (50.0) | 5/11 (45.5) | ||
Acute inpatient rehabilitation | 18/136 (13.2) | 8/50 (16.0) | 3/29 (10.3) | 1/14 (7.1) | 1/4 (25.0) | 2/11 (18.2) | ||
Skilled nursing facility or subacute rehabilitation | 20/136 (14.7) | 5/50 (10.0) | 6/29 (20.7) | 4/14 (28.6) | 0/4 (0) | 2/11 (18.2) | ||
Long-term acute care | 5/136 (3.7) | 2/50 (4.0) | 1/29 (3.5) | 2/14 (14.3) | 0/4 (0) | 0/11 (0) | ||
Other acute care facility | 7/136 (5.2) | 3/50 (6.0) | 3/29 (10.3) | 0/14 (0) | 0/4 (0) | 0/11 (0) | ||
Hospice | 2/136 (1.5) | 1/50 (2.0) | 0/29 (0) | 0/14 (0) | 0/4 (0) | 1/11 (9.1) | ||
Expired during hospitalization | 53/139 (38.1) | 20/50 (40.0) | 7/29 (24.1) | 3/14 (21.4) | 1/4 (25.0) | 1/11 (9.1) | ||
Modified Rankin Scale at discharge, median (IQR) | 4 (2–6) (n = 139) | 5 (3–6) (n = 51) | 4 (2–5) (n = 32) | 4 (2–5) (n = 14) | 1 (0–4) (n = 4) | 3 (2–4) (n = 10) | 0.20 | 0.07 |
Discharge mRS 0–2, no. (%) | 35/139 (25.2) | 11/51 (21.6) | 11/32 (34.4) | 4/14 (28.6) | 3/4 (75.0) | 3/10 (30.0) | 0.21 | 0.14 |
In-hospital mortality, no. (%) | 53/139 (38.1) | 20/50 (40.0) | 7/29 (24.1) | 3/14 (21.4) | 1/4 (25.0) | 1/11 (9.1) | 0.18 | 0.05 |