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Table 1 Demography and clinical characteristics of the cohort according to the presence of LVO

From: Relationship between leukocyte counts and large vessel occlusion in acute ischemic stroke

 

LVO present

(N = 167)

LVO absent

(N = 252)

P value

Demographic characteristics

 Age, years, median (IQR)

68 (61–79)

69 (59–77)

0.258

 Gender, female, % (n)

52.1 (87)

38.5 (97)

0.006

Elapsed times

 Onset-to-sample time, min, median (IQR)

83 (55–124)

88 (59–139)

0.313

 Sample-to-CTA time, min, median (IQR)

16 (6–25)

12 (5–28)

0.684

Parameters on admission

 NIHSS score on admission, median (IQR)

12 (7–17)

6 (4–8)

< 0.001

 On admission SBP, mmHg, median (IQR)

158 (140–177)

167 (145–180)

0.004

 On admission DBP, mmHg, median (IQR)

85 (78–96)

90 (80–100)

0.004

 Body temperature, oC, median (IQR)

36.4 (36.1–36.5)

36.4 (36.2–36.6)

0.069

 Blood glucose, mmol/L, median (IQR)

6.89 (5.90–8.10)

6.43 (5.61–8.35)

0.120

 INR, ratio, median (IQR)

1.02 (0.95–1.08)

0.99 (0.94–1.04)

0.003

Vascular risk factors

 Smoking, % (n), 60 missing

39.1 (52)

31.4 (71)

0.139

 Hypertension, % (n), 13 missing

81.6 (133)

77.8 (189)

0.352

 Diabetes mellitus, % (n), 19 missing

21.4 (34)

30.3 (73)

0.049

 Hyperlipidaemia, % (n), 36 missing

50.7 (76)

53.6 (125)

0.568

 Atrial fibrillation, % (n), 23 missing

32.9 (52)

17.2 (41)

< 0.001

 Coronary artery disease, % (n), 33 missing

27.7 (43)

23.4 (54)

0.332

 Chronic heart failure, % (n), 23 missing

15.0 (24)

7.6 (18)

0.019

 Previous stroke/TIA, % (n), 22 missing

17.6 (28)

25.2 (60)

0.074

 Malignancy, % (n), 31 missing

16.4 (25)

9.3 (22)

0.036

Therapy at stroke onset

 Antiplatelet, % (n), 23 missing

40.3 (62)

36.0 (87)

0.388

 Anticoagulant, % (n), 28 missing

17.6 (27)

9.7 (23)

0.021

 Lipid lowering, % (n), 23 missing

27.7 (43)

22.4 (54)

0.228

 Antihypertensive, % (n), 24 missing

72.9 (113)

66.7 (160)

0.190

 Antidiabetic, % (n), 24 missing

16.4 (25)

24.0 (58)

0.070

  1. Abbreviation: LVO large vessel occlusion; NIHSS National Institutes of Health Stroke Scale; SBP systolic blood pressure; DBP diastolic blood pressure; IQR interquartile range; INR International Normalized Ratio; TIA transient ischemic attack