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Table 2 B/M-values after ex vivo irradiation by 2 Gy in patients and healthy individuals

From: Ex vivo radiosensitivity is increased in non-cancer patients taking valproate

 

Healthy Individuals (n)

Patients (n)

p-value

Mean B/M-value (2 Gy)

0.415 ± 0.07 (62)

0.480 ± 0.09 (31)

.001

< 0.500 B/M

88.7% (55)

45.2% (14)

<.001

> 0.500 B/M

11.3% (7)

54.9% (14)

<.001

> 0.600 B/M

0.0% (0)

9.7% (3)

<.001

  1. Mean values of breaks per metaphase are given with standard deviations. Fractions of healthy individuals vs. patients with average B/M (B/M ≤ 0.500), increased (B/M > 0.500) and distinctly increased radiosensitivity (B/M > 0.600) are given