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Table 3 Performance Statistics for Stroke Mimic Prediction Scales

From: External validation of stroke mimic prediction scales in the emergency department

 

AUROC

(95% CI)

P value*

Cut off

Sensitivity (%)

(95% CI)

Specificity (%)

(95% CI)

PPV (%)

(95% CI)

NPV (%)

(95% CI)

LR+

(95% CI)

LR-

(95% CI)

FABS

0.612

(0.487–0.738)

0.151

2

24.6

(19.3–30.5)

52.9

(27.8–77.0)

88.1

(77.8–94.7)

4.7

(2.2–8.8)

0.52

(0.3–0.91)

1.42

(0.90–2.24)

Simplified FABS

0.608

(0.483–0.734)

0.139

2

25.4

(20–31.4)

52.9

(27.8–77.0)

88.4

(78.4–94.9)

4.8

(2.2–8.9)

0.54

(0.31–0.94)

1.41

(0.89–2.22)

TeleStroke Mimic Score

0.750

(0.629–0.872)

Reference

13.6

91.3

(86.9–94.5)

58.8

(32.9–81.6)

96.9

(93.7–98.8)

32.3

(16.7–51.4)

2.22

(1.25–3.92)

0.15

(0.08–0.26)

Khan Score

0.602

(0.517–0.686)

0.081

2

32.1

(26.2–38.4)

88.2

(63.6–98.5)

97.5

(91.2–99.7)

8.4

(4.8–13.5)

2.73

(0.73–10.2)

0.77

(0.63–0.93)

  1. AUROC indicates area under receiver operating characteristics curve; PPV positive predictive value; NPV negative predictive value; LR+ likelihood ratio of a positive test result; LR- likelihood ratio of a negative test result
  2. * P value of comparing paired AUC with Delong method