Table 4 Logistic regression analysis of MTHFR C677T in poor efficacy cases and controls
| Â | Cases, n (%) | Controls, n (%) | OR (95% CI) | P value |
|---|---|---|---|---|
Allele | ||||
 C | 63 (30.6) | 12 (10.2) | 1.000 (referrence) | – |
 T | 143 (69.4) | 106 (89.8) | 0.773 (0.693, 0.862) | < 0.001 |
Model type | ||||
 Codominant | ||||
  CC | 9 (8.7) | 1 (1.7) | 1.000 (referrence) | – |
  CT | 45 (43.7) | 10 (16.9) | 0.917 (0.734, 1.144) | 0.460 |
  TT | 49 (47.6) | 48 (81.4) | 0.862 (0.767, 0.970) | 0.017 |
Dominant | ||||
 CC | 9 (8.7) | 1 (1.7) | 1.000 (referrence) | – |
 CT + TT | 94 (91.3) | 58 (98.3) | 0.928 (0.867, 0.994) | 0.095 |
Recessive | ||||
 CC + CT | 54 (52.4) | 11 (18.6) | 1.000 (referrence) | – |
 TT | 49 (47.6) | 48 (81.4) | 0.585 (0.462, 0.741) | < 0.001 |