Table 1 Demographic data and symptoms in PD patients involved in this study
From: Association between NMD3 and symptoms of Parkinson’s disease in Chinese patients
NMD3 carriers (n = 178) | NMD3 wildtypes (n = 39) | p value | |
|---|---|---|---|
Age, mean (SD) | 57.03 (10.16) | 55.69 (10.24) | 0.461 |
Gender, female, N (%) | 73 (41.01) | 17 (43.59) | 0.907 |
Disease duration, mean (SD) | 4.79 (4.28) | 5.56 (3.89) | 0.275 |
Family history, N (%) | 17 (9.55) | 5 (12.82) | 0.550 |
Hoehn – Yahr staging, N (%) | 0.869 | ||
1.0 | 41 (23.03) | 10 (25.64) | |
1.5 | 29 (16.29) | 4 (10.26) | |
2.0 | 60 (33.71) | 14 (35.90) | |
2.5 | 32 (17.98) | 7 (17.95) | |
3.0 | 12 (6.74) | 4 (10.26) | |
4.0 | 4 (2.24) | 0 (0.00) | |
5.0 | 0 (0.00) | 0 (0.00) | |
MDS-UPDRS, mean (SD) | 48.34 (27.10) | 43.05 (20.51) | 0.175 |
Part I | 8.66 (6.16) | 7.51 (5.43) | 0.249 |
Part II | 11.60 (7.71) | 10.08 (5.81) | 0.168 |
Part III | 28.08 (17.45) | 25.46 (14.10) | 0.318 |
NMSS, mean (SD) | 36.23 (35.57) | 31.03 (27.42) | 0.315 |
SCOPA-AUT, mean (SD) | 10.92 (9.06) | 9.08 (8.56) | 0.233 |
PDQ-39, mean (SD) | 19.31 (17.84) | 16.23 (13.93) | 0.241 |
MMSE, mean (SD) | 26.31 (3.79) | 27.44 (2.89) | 0.042 |
MoCA, mean (SD) | 20.75 (6.68) | 23.15 (4.20) | 0.005 |