From: A ketogenic diet normalizes interictal cortical but not subcortical responsivity in migraineurs
HV | KD Before | KD After | |
---|---|---|---|
ST | 3.1 ± 4.6 | 2.5 ± 1.2 | 2.5 ± 1.5 |
PT | 14.1 ± 5.6 | 10.5 ± 4.6 | 11.1 ± 5.6 |
VAS (0–10) | 7.0 ± 2.1 | 7.1 ± 1.8 | 6.9 ± 1.2 |
Nociceptive Blink Reflex (nBR) | |||
Homolateral R2 onset (ms) | 32 ± 4.4 | 33.9 ± 7.9 | 32.9 ± 6.4 |
Homolateral R2 1st AUC block (μV x ms) | 1.2 ± 0.6 | 0.5 ± 0.3 § | 0.6 ± 0.3 § |
Homolateral R2 slope | - 0.15 ± 0.11 | 0.02 ± 0.18 § | 0.02 ± 0.17 § |
Contralateral R2 onset (ms) | 33.3 ± 4.6 | 33.7 ± 7.7 | 33.0 ± 5.9 |
Contralateral R2 1st AUC block (μV x ms) | 1.1 ± 0.7 | 0.5 ± 0.4 § | 0.5 ± 0.3 § |
Contralateral R2 slope | - 0.17 ± 0.37 | 0.005 ± 0.17 | 0.02 ± 0.11 |
Pain-related evoked potentials (PREP) | |||
N (ms) | 124.4 ± 16.3 | 127.0 ± 12.0 | 131.8 ± 18.0 |
P (ms) | 241.2 ± 59.1 | 218.3 ± 30.1 | 224.5 ± 26.8 |
N-P 1st amplitude block (μV) | 50.9 ± 28.5 | 39.1 ± 18.1 | 46.1 ± 19.1 |
N-P amplitude slope | - 6.9 ± 8.0 | 2.9 ± 11.0 § | - 9.1 ± 15.5 * |