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Table 2 Serum levels of cytokines and NOx in PD patients based on H-Y stage

From: Selected serum cytokines and nitric oxide as potential multi-marker biosignature panels for Parkinson disease of varying durations: a case-control study

H-Y scale

No. of patients

IFNγ

IL-10

TNFα

NOx

No signs of disease (0)

5

55.30 (±15.78)

25.69 (±4.58)

1.52 (±1.74)

16.53 (±6.25)

Unilateral disease (1)

11

40.66 (±6.69)

25.30 (±5.67)

4.97 (±6.13)

12.60 (±3.32)

Unilateral disease plus axial involvement (1.5)

5

46.60 (±8.24)

20.21 (±3.66)

10.30 (±12.29)

15.75 (±7.31)

Bilateral disease (2)

19

42.67 (±8.93)

23.88(±4.76)

3.53 (±4.94)

16.48 (±5.73)

Bilateral disease with recovery on pull test (2.5)

1

43.18 (±0)

22.17 (±0)

1.30 (±0)

25.24 (±0)

Mild to moderate bilateral disease (3)

22

41.76 (±9.99)

22.31 (±4.19)

2.65 (±3.314)

16.60 (±3.36)

Severe disability; still able to walk or stand unassisted (4)

6

54.04(±15.31)

25.14 (±7.37)

1.19 (±2.31)

13.33 (±1.84)

Wheelchair bound or bedridden unless aided (5)

3

40.15 (±7.61)

22.53 (±3.26)

−2.97 (±1.27)

18.58 (±3.38)

  1. All data are presented as mean ± standard deviation. The levels of cytokines are given in pg/ml whereas NOx levels are given in mmol/dm3. P < 0.05 was considered to be significant; Kruskal-Wallis H test