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Table 2 Clinical and laboratory findings on admission according to outcome in the two age groups

From: The prognostic value of total T3 after acute cerebral infarction is age-dependent: a retrospective study on 768 patients

Variables

Younger Group

(age < 65 yr)

P Value

Older Group

(age ≥ 65 yr)

P Value

Good functional outcome

(mRS ≤ 2) (n = 289)

Poor functional outcome (mRS > 2) (n = 38)

 

Good functional outcome

(mRS ≤2) (n = 377)

Poor functional outcome (mRS > 2) (n = 64)

 

Age (years)a

57 (51–61)

58 (52–62)

.169

75 (70–80)

78 (72–83)

.016

Sex (male, %)

191 (66.1%)

26 (68.4%)

.856

225 (59.7%)

29 (45.3%)

.040

Smoking (n,%)

142 (49.1%)

25 (65.8%)

.054

133 (35.3%)

15 (23.4%)

.064

Hyperlipidemia (n,%)

156 (54.0%)

21 (55.3%)

.881

105 (27.9%)

23 (40.0%)

.188

Coronary artery disease (n, %)

16 (5.5%)

5 (13.2%)

.081

33 (8.8%)

6 (9.4%)

.871

Diabetes mellitus (n, %)

75 (26.0%)

9 (23.7%)

.846

87 (23.1%)

17 (26.6%)

.633

Atrial fibrillation (n, %)

10 (3.5%)

6 (15.8%)

.006

41 (10.9%)

15 (23.4%)

.008

Previous stroke (n, %)

18 (6.2%)

3 (7.9%)

.722

56 (14.9%)

13 (20.3%)

.352

Transient ischemic attacks (n, %)

7 (2.4%)

2 (5.3%)

.281

13 (3.4%)

2 (3.1%)

.625

History of hypertension (n, %)

168 (58.1%)

23 (60.5%)

.862

270 (71.6%)

41 (64.1%)

.237

Systolic blood pressure (mm Hg)a

152 (131–170)

151 (135–165)

.525

161 (141–176)

158 (147–171)

.469

Diastolic blood pressure (mm Hg)a

85 (77–95)

83 (78–99)

.610

80 (71–88)

77 (67–87)

.276

Baseline NIHSS scoresa

2 (1–3)

11 (8–15)

≤.001

2 (1–4)

11 (8–14)

≤.001

TSH (IU/L)a

1.52 (1.01–2.05)

1.60 (1.14–1.96)

.951

1.73 (1.09–2.45)

1.36 (0.85–1.98)

.021

total T4 (μg/dL)a

6.37 (5.55–7.23)

6.88 (5.89–7.82)

.068

6.51 (5.79–7.47)

6.96 (6.03–7.95)

.051

total T3 (ng/mL)a

0.86 (0.73–0.98)

0.76 (0.63–0.92)

.013

0.82 (0.71–0.93)

0.71 (0.57–0.83)

≤.001

free T4 (ng/dL)a

1.07 (0.98–1.17)

1.11 (0.99–1.21)

.257

1.10 (1.00–1.20)

1.13 (1.03–1.29)

.040

free T3 (pg/mL)a

2.59 (2.31–2.93)

2.40 (2.01–2.66)

.001

2.49 (2.20–2.77)

2.21 (1.92–2.53)

≤.001

Initial WBC count (×109/L)a

7.10 (5.90–8.95)

8.60 (6.28–10.60)

.134

6.60 (5.60–8.30)

7.80 (6.30–8.40)

.175

Glucose on admission (mmol/L)a

7 (5.78–9.24)

8.19 (6.06–13.36)

.072

7.04 (5.81–9.36)

7.29 (5.85–10.72)

.516

C–reactive protein (mg/dL)a

1.40 (0.80–2.80)

1.7 (0.80–2.40)

.366

2.10 (0.90–5.90)

3.45 (1.25–8.13)

.876

  1. IQR interquartile range, NIHSS National Institutes of Health Stroke Scale, TSH thyroid–stimulating hormone, T4 thyroxine, T3 triiodothyronine, WBC white blood cell, mRS modified Rankin Scale
  2. aExpressed as median (IQR)
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BMC Neurology

ISSN: 1471-2377

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