Table 1 Baseline characteristics of patients with acute ischemic stroke (grouped by age)
Variables | Younger Age Group (age < 65 yr) (n = 327) | Older Age Group (age ≥ 65 yr) (n = 441) | P Value |
|---|---|---|---|
Age (years) (median, IQR) | 57 (51–61) | 76 (70–80) | ≤.001 |
Sex (male, %) | 217 (66.4%) | 254 (57.6%) | .016 |
Smoking (n,%) | 167 (51.1%) | 148 (33.6%) | ≤.001 |
Hyperlipidemia (n,%) | 177 (54.1%) | 128 (29.0%) | ≤.001 |
Coronary artery disease (n,%) | 21 (6.4%) | 39 (8.8%) | .225 |
Diabetes mellitus (n, %) | 84 (25.7%) | 104 (23.6%) | .553 |
Atrial fibrillation (n, %) | 16 (4.9%) | 56 (12.7%) | ≤.001 |
Previous stroke (n, %) | 21 (6.4%) | 69 (15.6%) | ≤.001 |
Transient ischemic attacks (n, %) | 9 (2.8%) | 15 (3.4%) | .679 |
History of hypertension (n, %) | 191 (58.4%) | 311 (70.5%) | .001 |
Systolic blood pressure (mmHg) (median, IQR) | 152 (132–170) | 160 (142–175) | ≤.001 |
Diastolic blood pressure (mmHg) (median, IQR) | 85 (77–95) | 80 (71–88) | ≤.001 |
Baseline NIHSS scores (median, IQR) | 2 (1–5) | 2 (1–5) | .703 |
Anterior circulation group | 229 (70.0%) | 304 (68.9%) | .752 |
Posterior circulation group | 91 (27.8%) | 125 (28.3%) | .935 |
TSH (IU/L) (median, IQR) | 1.52 (1.01–2.02) | 1.67 (1.05–2.40) | .002 |
total T4(μg/dL) (median, IQR) | 6.41 (5.58–7.27) | 6.59 (5.82–7.50) | .066 |
total T3 (ng/mL) (median, IQR) | 0.85 (0.72–0.98) | 0.81 (0.69–0.92) | ≤.001 |
free T4 (ng/dL) (median, IQR) | 1.07 (0.99–1.17) | 1.11 (1.00–1.21) | .011 |
free T3 (pg/mL) (median, IQR) | 2.54 (2.29–2.89) | 2.45 (2.16–2.74) | ≤.001 |
Initial WBC count (× 109/L) (median, IQR) | 7.20 (5.90–9.45) | 6.80 (5.60–8.30) | .051 |
Glucose on admission (mmol/L) (median, IQR) | 7.07 (5.82–9.59) | 7.09 (5.82–9.46) | .471 |
C-reactive protein (mg/dL) (median, IQR) | 1.40 (0.80–2.70) | 2.40 (0.90–5.98) | .001 |
poor functional outcome (mRS > 2) (n, %) | 38 (11.6%) | 64 (14.5%) | .282 |