From: Mortality & recurrent seizure risk after new-onset seizure in HIV-positive Zambian adults
Demographic | |
 Gender, female n (%) | 41 (43) |
 Age, mean (SD) | 36.9 (10.2) |
 Family history of epilepsy n (%) | 11 (12) |
 History of head injury n (%) | 2 (2) |
 History of severe malaria n (%) | 6 (6) |
 History of meningitis/encephalitis n (%) | 7 (7) |
 History of coma n (%) | 1 (1) |
 History of opportunistic infection (n = 94)a n (%) | 5 (5) |
 History of stroke (n = 94) a n (%) | 4 (4) |
Clinical | |
Seizure type n (%) | |
 Focal clonic | 13 (14) |
 Focal onset to bilateral tonic-clonic | 33 (35) |
 Tonic clonic | 1 (1) |
 Unknown onset bilateral tonic-clonic | 42 (44) |
 Unclassified | 6 (6) |
Presenting seizure severity n (%)b | |
 Status epilepticus | 50 (53) |
Glasgow Coma Score, mean (SD) | 14.3 (1.9) |
Karnofsky score < 50 at enrollment n (%) | 16 (17) |
WHO clinical stage n (%)a | |
 I or II | 12 (13) |
 III or IV | 81 (85) |
Current cART use n (%) | |
 Yes, less than a year | 13 (14) |
 Yes, more than a year | 17 (18) |
 No, defaulted | 7 (7) |
 No, never | 58 (61) |
CD4+ T-cell count at enrolment, mean cells/mm3(n = 89) a (SD) | 179 (185) |
Underlying seizure etiology c | |
CNS opportunistic infection n (%) | 21 (22) |
Other infection n (%) | 8 (8) |
Structural lesion n (%) | 25 (26) |
Hyponatremia (n = 91) n (%) | 47 (49) |
Likely secondary to another etiology | 17/47 (36) |
Unknown, n (%) | 20 (21) |