Characteristic | Value |
---|---|
Number of Patients | n = 86 |
Current age, median (range), y | 53 (15–84) |
Female sex, No. (%) | 77 (90%) |
NMO diagnosis, No. (%) | 64 (74%) |
NMOSD diagnosis, No. (%) | 22 (26%) |
Aquaporin-4 antibody positivity, No. (%) | 74 (86%) |
Age at onset, median (range), y | 43 (6–68) |
Overall disease duration, median (range), mo | 71 (7–535) |
Disease duration before receiving MMF, median (range), mo | 71 (6–444) |
Attack number before receiving MMF, median (range) | 5 (1–33) |
Duration of MMF treatment, median (range), mo | 20 (6–89) |
Abnormal autoantibodiesa, n (%) | 39 (45%) |
Coexisting with systemic autoimmune diseases | 29 (34%) |
Concurrent use of prednisone, n (%) | 65 (76%) |
treatment-naïve patients, n (%) | 21 (24%) |
Previous immunosuppressive agents: | |
Corticosteroidsb, n (%) | 33 (38%) |
Azathioprine, n (%) | 15 (17%) |
Cyclophosphamide, n (%) | 4 (5%) |
Rituximab, n (%) | 2 (2%) |
Tacrolimus (FK506) | 1 (1%) |
Methotrexate | 1 (1%) |
Previous immunomodulatory therapies: | |
β-interferons, n (%) | 6 (7%) |
hydroxychloroquine sulfate, n (%) | 2 (2%) |
Mitoxantrones, n (%) | 1 (1%) |