Table 1 Demographics and risk factors in patients and probands
Demographics | Total number | FD: R227Q | D313Y |
|---|---|---|---|
Patients | 178 | 1 | 1 |
Men | 73 (40,7 %) | 1 | 0 |
Age at recruitment | 48,4a | 41 | 52 |
Age at onset (symptomatic) | 43,3a | 48 | |
Age at onset (WMLs) | 43,5a | 41 | |
Risk factors | |||
Hypertension | 106 (59,5 %) | 1 | 1 |
Diabetes | 11 (6,1 %) | 0 | 0 |
Atrial fibrillation | 3 (1,7 %) | 0 | 0 |
Dyslipidemia | 83 (46,6 %) | 0 | 1 |
Smoking | 40 (22,4 %) | 0 | 0 |
Drinking habit | 13 (7,3 %) | 0 | 0 |
Oral contraception | 5 (4,7 %) | NA | 0 |
Hyperhomocysteine | 22 (12,3 %) | 1 | 1 |
Overweight/obesity | 68 (38,2 %) | 0 | 1 |
Fabry feature | |||
Acroparesthesia | 13 (7,3 %) | 1 | 0 |
Angiokeratoma | 0 | 0 | 0 |
Cornea verticillata | 1 (0,5 %) | 0 | 0 |
CKD/Proteinuria | 22 (12,3 %) | 0 | 1 |
Cardiac involvement | 32 (17,97 %) | 1 | 1 |