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Fig. 2 | BMC Neurology

Fig. 2

From: Correlation of Tc-99 m ethyl cysteinate dimer single-photon emission computed tomography and clinical presentations in patients with low cobalamin status

Fig. 2

Single-photon emission computed tomography (SPECT) correlates with clinical presentations and disease severity of cobalamin-deficient patients. (a) A case with anxiety disorder but preserved cognition. Clinical Dementia Rating (CDR) = 0. SPECT shows hypoperfusion in right basal ganglia (asterisk) and bilateral temporal tips (arrow heads; Patient #12). (b) A case with prominent dysexecutive syndrome. CDR = 0.5. SPECT shows hypoperfusion in right basal ganglia (asterisk) and left dorsolateral prefrontal cortex, in addition to temporal regions. (arrow heads; Patient #4). (c) A case with clinical diagnosis of dementia. CDR = 1. SPECT shows bilateral, more pronounced in the left, thalamus (asterisk) and fronto-temporal regions hypoperfusion (arrow heads; Patient #1)

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