| Follow-up weeks | BITT |  | BoNT-A |  | BoNT-A additional effect |  | |||
---|---|---|---|---|---|---|---|---|---|---|
Yes (BoNT-A + BITT and BITT-only) | No (BoNT-A-only and control) | p-value | Yes (BoNT-A + BITT and BoNT-A-only) | No (BITT-only and control) | p-value | BoNT-A + BITT | BITT-only | p-value | ||
n = 8 | n = 6 | n = 6 | n = 8 | n = 4 | n = 4 | |||||
OSAS percentage of use both hands | 0 | 80.6 (4.6) | 72.4 (5.4) | Â | 69.7 (5.4) | 83.2 (4.6) | Â | 76.7 (4.7) | 84.5 (4.7) | Â |
6 | 78.6 (3.9) | 68.3 (4.7) | 0.662 | 66.7 (4.6) | 80.1 (4.0) | 0.980 | 73.1 (4.2) | 84.1 (4.2) | 0.580 | |
12 | 76.6 (6.7) | 59.5 (7.9) | 0.213 | 62.5 (7.9) | 73.6 (6.7) | 0.724 | 73.8 (5.8) | 79.4 (5.8) | 0.758 | |
Treading beads p -value | 18 | 81.7 (4.2) | 72.9 (5.0) | 0.922 | 75.5 (4.9) | 79.1 (4.3) | 0.049 | 81.8 (5.1) | 81.5 (5.1) | 0.216 |
24 | 80.3 (3.5) | 69.1 (4.3) | 0.546 | 73.1 (4.1) | 76.4 (3.6) | 0.041 | 80.9 (2.8) | 79.7 (2.8) | 0.123 | |
overall | Â | Â | 0.716 | Â | Â | 0.072 | Â | Â | 0.156 | |
OSAS Quality grasp wrist | 0 | 2.32 (0.26) | 2.01 (0.31) | Â | 2.12 (0.31) | 2.21 (0.260 | Â | 2.16 (0.35) | 2.49 (0.35) | Â |
6 | 2.43 (0.26) | 2.51 (0.31) | 0.219 | 2.94 (0.31) | 2.00 (0.27) | 0.003 | 2.60 (0.35) | 2.26 (0.35) | 0.114 | |
Treading beads (1–5) SDD 0.65p -value | 12 | 2.55 (0.26) | 2.59 (0.31) | 0.397 | 3.05 (0.31) | 2.10 (0.26) | 0.020 | 2.81 (0.35) | 2.29 (0.35) | 0.149 |
18 | 2.36 (0.26) | 2.32 (0.31) | 0.437 | 2.56 (0.31) | 2.12 (0.27) | 0.128 | 2.48 (0.35) | 2.25 (0.35) | 0.280 | |
24 | 2.48 (0.26) | 2.40 (0.32) | 0.500 | 2.66 (0.31) | 2.21 (0.27) | 0.127 | 2.54 (0.35) | 2.42 (0.35) | 0.387 | |
overall | Â | Â | 0.542 | Â | Â | 0.028 | Â | Â | 0.464 | |
OSAS Quality grasp wrist | 0 | 2.26 (0.27) | 2.16 (0.32) | Â | 2.29 (0.32) | 2.13 (0.27) | Â | 2.10 (0.38) | 2.41 (0.38) | Â |
6 | 2.49 (0.27) | 2.27 (0.32) | 0.665 | 2.98 (0.32) | 1.79 (0.27) | 0.001 | 2.75 (0.38) | 2.23 (0.38) | 0.059 | |
Pop-Onz (1–5) SDD 0.55 p -value | 12 | 2.50 (0.27) | 2.49 (0.32) | 0.802 | 3.10 (0.32) | 1.89 (0.27) | 0.000 | 3.01 (0.38) | 2.00 (0.38) | 0.028 |
18 | 2.33 (0.27) | 2.69 (0.32) | 0.164 | 2.94 (0.32) | 2.08 (0.27) | 0.032 | 2.51 (0.38) | 2.16 (0.38) | 0.175 | |
24 | 2.32 (0.27) | 2.37 (0.32) | 0.385 | 2.61 (0.32) | 2.08 (0.27) | 0.043 | 2.28 (0.38) | 2.36 (0.38) | 0.315 | |
overall | Â | Â | 0.553 | Â | Â | 0.011 | Â | Â | 0.189 | |
OSAS Quality hold wrist | 0 | 2.44 (0.26) | 2.23 ((0.31) | Â | 2.19 (0.31) | 2.48 (0.26) | Â | 2.23 (0.34) | 2.65 (0.34) | Â |
Treading beads (1–5) SDD 0.71 p -value | ||||||||||
6 | 2.44 (0.26) | 2.62 (0.32) | 0.218 | 3.00 (0.31) | 2.06 (0.27) | 0.000 | 2.71 (0.34) | 2.17 (0.34) | 0.020 | |
12 | 2.58 (0.26) | 2.60 (0.31) | 0.445 | 2.86 (0.31) | 2.31 (0.26) | 0.006 | 2.76 (0.34) | 2.40 (0.34) | 0.055 | |
18 | 2.53 (0.26) | 2.39 (0.32) | 0.822 | 2.68 (0.31) | 2.23 (0.27) | 0.017 | 2.72 (0.34) | 2.34 (0.34) | 0.050 | |
24 | 2.47 (0.26) | 2.34 (0.32) | 0.815 | 2.50 (0.31) | 2.31 (0.27) | 0.117 | 2.37 (0.34) | 2.58 (0.34) | 0.573 | |
overall | Â | Â | 0.728 | Â | Â | 0.003 | Â | Â | 0.086 | |
OSAS Quality hold wrist | 0 | 2.35 (0.27) | 2.11 (0.31) | Â | 2.16 (0.31) | 2.30 (0.27) | Â | 2.07 (0.36) | 2.63 (0.36) | Â |
6 | 2.68 (0.27) | 2.37 (0.32) | 0.829 | 3.12 (0.31) | 1.93 (0.27) | 0.000 | 2.99 (0.36) | 2.36 (0.36) | 0.007 | |
Pop-Onz (1–5) SDD 0.87 p -value | ||||||||||
12 | 2.62 (0.27) | 2.45 (0.31) | 0.781 | 2.94 (0.31) | 2.13 (0.27) | 0.001 | 2.87 (0.36) | 2.37 (0.36) | 0.010 | |
18 | 2.33 (0.27) | 2.65 (0.32) | 0.051 | 2.77 (0.31) | 2.21 (0.27) | 0.014 | 2.33 (0.36) | 2.34 (0.36) | 0.198 | |
24 | 2.34 (0.27) | 2.24 (0.31) | 0.605 | 2.37 (0.31) | 2.20 (0.27) | 0.271 | 2.13 (0.36) | 2.55 (0.36) | 0.735 | |
overall | Â | Â | 0.215 | Â | Â | 0.000 | Â | Â | 0.024 |