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Table 2 Study characteristics of studies describing consecutive patients suspected of CVT

From: D-dimer for the exclusion of cerebral venous thrombosis: a meta-analysis of low risk patients with isolated headache

 

Study design

All/isolated headache patients

D-dimer test

Cut-off value

Imaging

Missing information

Tardy et al. [16]

Prospective

52/23

ELISA Vidas assay

>0.5 μg/ml

MRA

None missing

Kosinski, et al. [14]

Prospective

343/291

2nd generation latexagglutination

>0.5 μg/ml

MRA or CTV

None missing

Meng, et al. [17]

Prospective

233/173

Immuno- turbidimetric assay

>0.5

MRI/MRV

None missing

Tanislav et al. [23]

Retrospective

239/X

Turbidimetric

>0.19 μg/ml

CTV or MRV

Isolated headache unclear

Ghaffarpour et al. [24]

Prospective

104/X

Conventional ELISA

>0.5 μg/ml

 

Isolated headache unclear

Gouda, Sabry [21]

Prospective

104/X

2nd generation latexagglutination

>0.5 μg/ml

TOF MRA

isolated headache unclear in non CVT group

Lalive, et al. [20]

Prospective

54/X

ELISA Vidas assay

>0.5 μg/ml

MRA

Isolated headache unclear in non CVT group

Cucchiara, et al. [22]

Prospective

31/X

ELISA Vidas assay

>0.5 μg/ml

MRV

Isolated headache unclear in non CVT group

  1. MRA MR angiography, MRV MR venography, CTV CT venography, TOF time of flight, CVT cerebral venous thrombosis