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Table 2 Comparison of clinical outcomes according to the statin starting time

From: Early statin use in ischemic stroke patients treated with recanalization therapy: retrospective observational study

 

Statin use

No use

P trend*

D1

D2

D ≥ 3

(N = 170)

(N = 45)

(N = 70)

(N = 52)

3-Month functional outcome

     

Better primary outcome (mRS, 0-1)

19 (42.2 %)

26 (37.1 %)

18 (34.6 %)

38 (22.4 %)

0.002

Favorable outcome (mRS, 0-2)

26 (57.8 %)

30 (42.9 %)

29 (55.8 %)

57 (33.5 %)

0.004

Neurologic outcome during hospitalization

     

Neurologic improvementa

24 (53.3 %)

39 (55.7 %)

38 (73.1 %)

84 (49.4 %)

0.87

Neurologic deteriorationb

7 (15.6 %)

10 (14.3 %)

1 (1.9 %)

45 (26.5 %)

0.02

Ischemic recurrence

8 (17.8 %)

11 (15.7 %)

4 (7.7 %)

27 (15.9 %)

0.84

Symptomatic hemorrhagic transformationc

1 (2.2 %)

2 (2.9 %)

0 (0.0 %)

17 (10.0 %)

0.01

  1. See footnotes of Table 1 for definitions and abbreviations
  2. Values represent number of patients (percentage)
  3. *P values were obtained by Mantel-Haenszel test for trend
  4. aNeurologic improvement was defined as a decrease of ≥ 4 NIHSS score or a NIHSS score of 0 or 1 at discharge
  5. bNeurologic deterioration was defined as an increase of ≥ 4 NIHSS score
  6. cThe definition of symptomatic hemorrhagic transformation was adopted from the SITS-MOST study [24]
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BMC Neurology

ISSN: 1471-2377

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