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Table 1 Comparison of baseline characteristics according to the statin starting time

From: Early statin use in ischemic stroke patients treated with recanalization therapy: retrospective observational study

Variables

Statin use

No use

P value*

D1

D2

D ≥ 3

(N = 45)

(N = 70)

(N = 52)

(N = 170)

Age, years, mean ± SD

67.6 ± 11.6

69.5 ± 12.0

68.0 ± 12.5

69.6 ± 12.7

0.69

Male sex

30 (66.7 %)

36 (51.4 %)

31 (59.6 %)

91 (53.5 %)

0.34

Time from onset to arrival, hours, mean ± SD

1.4 ± 1.3

1.6 ± 1.3 s

1.6 ± 1.4

1.5 ± 1.2

0.66

History of stroke

12 (26.7 %)

12 (17.1 %)

6 (11.5 %)

46 (27.1 %)

0.07

Hypertension

28 (62.2 %)

42 (60.0 %)

32 (61.5 %)

95 (55.9 %)

0.80

Diabetes mellitus

10 (22.2 %)

13 (18.6 %)

9 (17.3 %)

30 (17.6 %)

0.91

Atrial fibrillation

15 (33.3 %)

37 (52.9 %)

12 (23.1 %)

54 (31.8 %)

0.003

Premorbid statin use

8 (17.8 %)

10 (14.3 %)

6 (11.5 %)

15 (8.8 %)

0.33

Baseline NIHSS score, median (IQR)

15 (7–18)

11 (6-20)

12 (7.5–17)

15 (9–20)

0.14

Stroke subtype

    

0.002

 LAA

20 (44.4 %)

27 (38.6 %)

21 (40.4 %)

42 (24.7 %)

 

 CE

13 (28.9 %)

39 (55.7 %)

22 (42.3 %)

96 (56.5 %)

 

 UD or OD

12 (26.7 %)

4 (5.7 %)

9 (17.3 %)

32 (18.8 %)

 

Recanalization modality

    

0.007

 IV-only

15 (33.3 %)

28 (40.0 %)

13 (25.0 %)

30 (17.6 %)

 

 IA-only

15 (33.3 %)

15 (21.4 %)

20 (38.5 %)

55 (32.4 %)

 

 Combined treatment

15 (33.3 %)

27 (38.6 %)

19 (36.5 %)

85 (50.0 %)

 
  1. Values represent number of patients (percentage) if not indicated
  2. *P values were obtained by Pearson χ2 test, ANOVA test, and Kruskal-Wallis test according to characteristics of variables
  3. LAA is the abbreviation for large artery atherosclerosis; CE for cardioembolism, UD or OD for undetermined or other determined, IV-only for intravenous thrombolysis-only, IA-only for intra-arterial treatment-only, and IQR for interquartile range