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Figure 3 | BMC Neurology

Figure 3

From: Attenuation of myogenic orofacial nociception and mechanical hypersensitivity by viral mediated enkephalin overproduction in male and female rats

Figure 3

Experiment #2: Human met-enkephalin in the rat trigeminal ganglia after injection of herpes virus expressing the enkephalin transgene or a control virus. A single randomly chosen trigeminal ganglia was removed three weeks after injection (see Experiment 2, Table 1) and the human enkephalin protein was quantitated by ELISA. Measurements were made in both male (panel A) and female (panel B) rats. Groups received either a vehicle injection or an injection of virus that did not contain an enkephalin transgene (control virus, SHZ) or a virus that had an enkephalin transgene (SHPE). The vehicle and SHZ control groups were not significantly different than the zero ng met-enkephalin standard provided in the ELISA kit and the values obtained for these groups were considered background and combined in Figure 3A and 3B. Values are the means ± SEM. An asterisk indicates a significant difference (p < 0.05) between the vehicle & SHZ control groups versus the SHPE virus group. See Table 2 for the number of animals per group.

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BMC Neurology

ISSN: 1471-2377

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