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Table 1 Baseline characteristics for sex in unmatched and matched cohort (Matched variables are marked bold)

From: Impact of sex in stroke thrombolysis: a coarsened exact matching study

 

Unmatched

 

Matched

 
 

Female

Male

P

Female

Male

P §

N

668

723

 

502

436

 

Age*

75.3 (12.1)

68.8 (12.7)

<0.001

74.4 (11.0)

74.3 (10.9)

0.939

NIHSS

12 (7; 17)

10 (6; 15)

<0.001

12 (7; 17)

12 (6; 17)

0.506

Hemisphere, left

402 (60.2%)

412 (57.0%)

0.231

317 (63.1%)

275 (63.1%)

>0.999

Hypertension

555 (83.1%)

565 (78.1%)

0.021

433 (86.3)

376 (86.3%)

>0.999

Diabetes

170 (25.4%)

188 (26.0%)

0.854

106 (21.1%)

92 (21.1%)

>0.999

Atrial fibrillation

272 (40.7%)

185 (25.6%)

<0.001

185 (36.9%)

161 (36.9%)

>0.999

Current smoker

64 (9.6%)

146 (20.2%)

<0.001

33 (6.6%)

29 (6.6%)

>0.999

CHD

114 (17.1%)

188 (26.0%)

<0.001

67 (13.3%)

58 (13.3%)

>0.999

Previous Stroke

135 (20.2%)

155 (21.4%)

0.597

64 (12.7%)

56 (12.7%)

>0.999

TTT [min]

140 (105; 180)

140 (105; 180)

0.615

140 (105; 180)

140 (110; 180)

0.504

Hyperlipidemia

195 (29.2%)

265 (35.4%)

0.014

142 (28.3%)

115 (26.3%)

0.557

Statin use

137 (20.5%)

202 (27.9%)

0.001

103 (20.5%)

96 (22.0%)

0.576

Antithrombotics

298 (44.6%)

340 (47%)

0.389

212 (42.2%)

216 (49.6%)

0.026

OAC

44 (6.6%)

31 (4.3%)

0.074

27 (5.4%)

21 (4.7%)

0.767

Systolic BP [mmHg]

160.6 (22.1)

159.1 (22.1)

0.202

161.5 (21.0)

160.3 (22.5)

0.408

Diastolic BP [mmHg]

86.1 (16.0)

88.2 (15.1)

0.009

86.1 (15.6)

86.3 (15.5)

0.856

Glucose [mg/dl]

121 (105; 148)

120(105; 147)

0.434

120 (105; 147)

121 (106; 144)

0.706

Platelet [count/nl]

263 (215; 313)

233 (193; 283)

<0.001

266 (216; 313)

234 (192; 277)

<0.001

  1. Numbers are mean (standard deviation) or median (25/75 interquartile range) or counts (percentages).
  2. NIHSS indicates National Institutes of Health Stroke Scale, CHD coronary heart disease, TTT time to treatment, OAC oral anticoagulation, BP Blood Pressure.
  3. *Student’s T-Test.
  4. Mann Whitney-U Test.
  5. Chi-Square/Fisher-Exact-Test.
  6. §considering match weights.