Table 6 The genotype frequencies of TIMP-2 -418G > C polymorphism according to age of participants
Age <18 | Age <18 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Characteristic | Control (n = 102) | Moyamoya (n = 56) | AOR (95% CI) | P a | P b | Control (n = 141) | Moyamoya (n = 51) | AOR (95% CI) | P a | P b |
TIMP2 -418G > C | ||||||||||
GG | 66 (64.7) | 29 (51.8) | 1.00 (reference) | 110 (78.0) | 27 (52.9) | 1.00 (reference) | ||||
GC | 31 (30.4) | 23 (41.1) | 1.69 (0.84-3.42) | 0.14 | 0.28 | 31 (22.0) | 23 (45.1) | 2.99 (1.49-5.98) | <.01 | 0.01 |
CC | 5 (4.9) | 4 (7.1) | 1.91 (0.47-7.75) | 0.37 | 0.49 | 0 | 1 (2.0) | NA | NA | |
Dominant | 1.69 (0.86-3.29) | 0.13 | 0.28 | 3.10 (1.56-6.18) | <.01 | 0.01 | ||||
Recessive | 1.36 (0.34-5.38) | 0.67 | 0.67 | NA | NA | |||||