Table 4 The combined genotype frequencies of MMP polymorphisms according to age of participants
Age <18 | Age <18 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Characteristic | Control (n = 102) | Moyamoya (n = 56) | AOR (95% CI) | P a | P b | Control (n = 141) | Moyamoya (n = 51) | AOR (95% CI) | P a | P b |
MMP-2 -1575/-1306 | ||||||||||
GG/CC | 88 (86.3) | 46 (82.1) | 1.00 (reference) | 122 (86.5) | 46 (90.2) | 1.00 (reference) | ||||
GG/CT | 0 (0.0) | 0 (0.0) | NA | NA | 0 (0.0) | 0 (0.0) | NA | NA | ||
GG/TT | 0 (0.0) | 0 (0.0) | NA | NA | 0 (0.0) | 0 (0.0) | NA | NA | ||
GA/CC | 2 (2.0) | 7 (12.5) | 6.70 (1.34-33.60) | 0.01 | 0.02 | 10 (7.1) | 0 (0.0) | 0.13 (0.01-2.19) | 0.07 | 0.14 |
GA/CT | 12 (11.8) | 3 (5.4) | 0.48 (0.13-1.78) | 0.39 | 0.39 | 9 (6.4) | 5 (9.8) | 1.47 (0.47-4.63) | 0.54 | 0.54 |
GA/TT | 0 (0.0) | 0 (0.0) | NA | NA | 0 (0.0) | 0 (0.0) | NA | NA | ||
AA/CC | 0 (0.0) | 0 (0.0) | NA | NA | 0 (0.0) | 0 (0.0) | NA | NA | ||
AA/CT | 0 (0.0) | 0 (0.0) | NA | NA | 0 (0.0) | 0 (0.0) | NA | NA | ||
AA/TT | 0 (0.0) | 0 (0.0) | NA | NA | 0 (0.0) | 0 (0.0) | NA | NA | ||
MMP-9 -1562/Q279R | ||||||||||
CC/GG | 25 (24.8) | 22 (39.3) | 1.00 (reference) | 45 (31.9) | 19 (37.3) | 1.00 (reference) | ||||
CC/GA | 45 (44.1) | 21 (37.5) | 0.53 (0.24-1.16) | 0.11 | 0.28 | 57 (40.4) | 18 (35.3) | 0.72 (0.34-1.55) | 0.40 | 0.62 |
CC/AA | 9 (8.8) | 2 (3.6) | 0.24 (0.05-1.25) | 0.09 | 0.28 | 14 (9.9) | 3 (5.9) | 0.44 (0.11-1.76) | 0.25 | 0.62 |
CT/GG | 15 (14.7) | 5 (8.9) | 0.50 (0.15-1.71) | 0.27 | 0.44 | 14 (9.9) | 7 (13.7) | 1.32 (0.45-3.91) | 0.62 | 0.62 |
CT/GA | 7 (6.9) | 4 (7.1) | 0.59 (0.14-2.43) | 0.46 | 0.46 | 11 (7.8) | 3 (5.9) | 0.66 (0.16-2.66) | 0.56 | 0.62 |
CT/AA | 0 (0.0) | 0 (0.0) | NA | NA | 0 (0.0) | 0 (0.0) | NA | NA | ||
TT/GG | 1 (1.0) | 2 (3.6) | 3.73 (0.24-58.01) | 0.35 | 0.44 | 0 (0.0) | 1 (2.0) | NA | NA | |
TT/GA | 0 (0.0) | 0 (0.0) | NA | NA | 0 (0.0) | 0 (0.0) | NA | NA | ||
TT/AA | 0 (0.0) | 0 (0.0) | NA | NA | 0 (0.0) | 0 (0.0) | NA | NA | ||