Figure 1

Quantification of the central canal perimeter +/- 1 mm-5 mm from the lesion epicenter 450 days after injury, with representative toluidine blue stained transverse sections of rat spinal cord for each distance. Extensive dural fibrosis and intraparenchymal cavitations are evident at the epicenter of the injury, which are reminiscent of human syringomyelia. Central canal dilation is more marked cranial to the epicenter of injury and is evident up to 5 mm cranial to epicenter of the injury. Asterisks indicate significance at p < 0.05. Magnification = 10×.