| Normal PCA | Foetal-type PCA |
---|---|---|
 | (n = 96) | (n = 16) |
Age (years) | 69 (9) | 68 (9) |
Sex (male) | 72 (75%) | 10 (63%) |
Education* | 5.0 [4.0–6.0] | 4.0 [3.3–4.8] |
Vascular risk factors | Â | Â |
Treated hypertension | 71 (75%) | 10 (65%) |
Systolic blood pressure (mm Hg) | 168 (27) | 174 (28) |
Diastolic blood pressure (mm Hg) | 86 (13) | 87 (13) |
Cardiac failure | 3 (3%) | 1 (6%) |
Angina pectoris in past 6Â months | 7 (7%) | 0 (0%) |
Previous myocardial infarction | 19 (20%) | 3 (19%) |
Previous CABG | 17 (18%) | 2 (13%) |
Atrial fibrillation | 4 (4%) | 0 (0%) |
Other cardiac embolic source | 4 (4%) | 0 (0%) |
Type 2 diabetes mellitus | 16 (17%) | 2 (13%) |
Type 1 diabetes mellitus | 4 (4%) | 1 (6%) |
Peripheral arterial disease | 17 (18%) | 3 (19%) |
Current smoker | 32 (34%) | 3 (19%) |
Ex-smoker | 55 (59%) | 9 (56%) |
Treated hyperlipidaemia | 72 (76%) | 13 (81%) |
Cholesterol (mmol/L) | 4.7 (1.1) | 4.9 (1.4) |
Imaging | Â | Â |
MRA | 68 (71%) | 11 (69%) |
CTA | 28 (29%) | 5 (31%) |
Treatment | Â | Â |
CEA | 44 (46%) | 10 (63%) |
CAS | 52 (54%) | 6 (38%) |
Symptomatic side | Â | Â |
Left carotid artery | 44 (46%) | 10 (63%) |
Degree of symptomatic carotid artery stenosis†|  |  |
50–69% | 13 (14%) | 2 (13%) |
70–99% | 83 (87%) | 14 (88%) |
Degree of contralateral carotid artery stenosis†|  |  |
<50% | 58 (60%) | 13 (81%) |
50–69% | 12 (13%) | 0 (0%) |
70–99% | 15 (16%) | 2 (13%) |
Occluded | 7 (7%) | 1 (6%) |
Unknown | 4 (4%) | 0 (0%) |
Anatomy anterior part circle of Willis | Â | Â |
Ipsilateral A1 present | 80 (83%) | 15 (94%) |
Anterior communicating artery present | 95 (99%) | 15 (94%) |
Contralateral A1 present | 86 (90%) | 15 (94%) |
Most recent ipsilateral event‡ |  |  |
Amaurosis fugax | 24 (26%) | 2 (13%) |
Transient ischaemic attack | 34 (37%) | 4 (25%) |
Ischaemic stroke | 29 (32%) | 9 (56%) |
Retinal infarction | 3 (3%) | 1 (6%) |
Unknown | 2 (2%) | 0 (0%) |
NIHSS at randomization | 0 (0–1) | 0.5(0–1) |
Modified Rankin score at randomization | Â | Â |
0–2 | 85 (90%) | 15 (94%) |
3–5§ | 10 (11%) | 1 (6%) |
Unknown | 1 (0%) | 0 (0%) |