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Table 1 Molecular profiles of patients with perfusion-diffusion mismatch (PDM) and clinical-diffusion mismatch (CDM) who received or did not receive thrombolytic treatment

From: Interleukin-10 facilitates the selection of patients for systemic thrombolysis

 

PDM (n = 100)

CDM (n = 184)

 

NO (n = 21)

YES (n = 79)

p

NO (n = 92)

YES (n = 92)

p

NSE (ng/mL)

22.4 ± 9.0

20.7 ± 6.1

0.449

24.6 ± 8.3

21.4 ± 5.8

0.002

IL-10 (pg/mL)

8.8 ± 7.0

22.5 ± 14.9

<0.0001

8.6 ± 8.0

30.9 ± 14.7

<0.0001

Glutamate (μM)

150.9 ± 102.2

207.7 ± 177.9

0.290

152.5 ± 91.5

226.6 ± 186.9

0.031

IL-6 (pg/mL)

9.9 ± 8.9

11.9 ± 8.6

0.250

20.9 ± 17.7

14.2 ± 7.6

0.109

TNF-α (pg/mL)

10.3 ± 6.3

11.5 ± 8.2

0.774

12.4 ± 6.6

18.4 ± 12.6

0.003

MMP-9 (ng/mL)

24.0 ± 16.6

21.0 ± 11.9

0.745

29.6 ± 18.4

20.2 ± 8.4

<0.0001