Table 2 Prevalence of Seizure, unadjusted and adjusted Prevalence Risk Ratios (PRR) for breakthrough seizures
Number with seizure n/N | Percentage with seizure (%) | Unadjusted PRR 95% CI | p-value | Adjusted PRR**, 95% CI | p-value | |
|---|---|---|---|---|---|---|
Sex | ||||||
Female | 82/111 | 73.9 | 0.96 (0.83,1.11) | 0.96 (0.84,1.11) | ||
Male | 111/145 | 76.6 | 1.0 | 0.618 | 1.0 | 0.581 |
Age group | ||||||
18-20 | 78/97 | 80.4 | 1.0 | 1.0 | ||
21-29 | 59/80 | 73.8 | 0.92 (0.78, 1.08) | 0.301 | 0.91 (0.76,1.08) | 0.266 |
30-44 | 39/56 | 69.6 | 0.87 (0.71,1.06) | 0.157 | 0.86 (0.68, 1.08) | 0.181 |
45+ | 17/23 | 73.9 | 0.92 (0.71,1.19) | 0.529 | 0.92 (0.65,1.30) | 0.633 |
Marital status | ||||||
Never married/single | 148/195 | 75.9 | 1.0 | 1.0 | ||
Married | 35/45 | 77.8 | 1.02 (0.86,1.22) | 0.784 | 1.06 (0.85,1.31) | 0.602 |
Divorced/separated/widowed | 10/16 | 62.5 | 0.82 (0.56, 1.21) | 0.327 | 0.87 (0.56,1.34) | 0.531 |
Level of education | ||||||
None | 13/17 | 76.5 | 1.0 | 1.0 | ||
Primary (P1-P7) | 77/101 | 76.2 | 1.0 (0.75,1.38) | 0.983 | 0.98 (0.73,1.30) | 0.864 |
Secondary (S1-S6) | 77/102 | 75.5 | 0.99 (0.74,1.31) | 0.930 | 0.97 (0.73,1.30) | 0.842 |
Tertiary | 26/36 | 72.2 | 0.94 (0.68, 1.32) | 0.737 | 0.98 (0.70,1.37) | 0.897 |
Duration on Treatment | ||||||
<1 years | 30/32 | 93.8 | 1.0 | 1.0 | ||
1-5 | 109/150 | 72.7 | 0.78 (0.68,0.89) | <0.000 | 0.79 (0.68, 0.91) | 0.001 |
5+ | 54/74 | 73.0 | 0.78 (0.66,0.92) | 0.004 | 0.82 (0.68,0.98) | 0.025 |
Number of drugs taken | ||||||
One drug | 64/83 | 77.1 | 1.0 | 1.0 | ||
Two drugs | 94/124 | 75.8 | 0.98 (0.84,1.15) | 0.828 | 0.98 (0.85,1.15) | 0.839 |
Three drugs | 35/49 | 71.4 | 0.93 (0.75,1.15) | 0.481 | 0.93 (0.76,1.15) | 0.525 |
Doses missed | ||||||
None | 136/187 | 72.7 | 1.0 | 1.0 | ||
1-3 doses | 23/32 | 71.9 | 0.99 (0.78,1.25) | 0.921 | 1.04 (0.82,1.30) | 0.764 |
> 3 doses | 34/37 | 91.9 | 1.26 (1.11,1.44) | <0.0001 | 1.33 (1.16,1.52) | <0.000 |
Hours slept (hours) | ||||||
<=6 | 18/26 | 69.2 | 1.0 | 1.0 | ||
7-9 | 109/145 | 75.2 | 1.09 (0.83,1.43) | 0.555 | 1.11(0.83,1.49) | 0.467 |
10+ | 66/85 | 77.7 | 1.12 (0.85,1.49) | 0.424 | 1.18 (0.87,1.59) | 0.283 |