From: Cerebral hemodynamics and endothelial function in patients with Fabry disease
Parameter | Healthy volunteers (n = 17) | Patients with FD (n = 10) | p value | |
---|---|---|---|---|
Right middle cerebral artery | ||||
Mean blood flow velocity (cm/s) | 56.07 ± 10.36 | 56.82 ± 15.53 | 0.9 | |
Maximum blood flow velocity (cm/s) | 87.58 ± 16.48 | 86.64 ± 21.66 | 0.9 | |
Pulsatility index | 0.84 ± 0.15 | 0.80 ± 0.18 | 0.57 | |
Apnea Test (%) | 56.79 ± 15.68 | 47.25 ± 15.36 | 0.21 | |
Left middle cerebral artery | ||||
Mean blood flow velocity (cm/s) | 59.21 ± 14.15 | 58.15 ± 16.95 | 0.9 | |
Maximum blood flow velocity (cm/s) | 94.30 ± 22.09 | 88.85 ± 26.64 | 0.6 | |
Pulsatility index | 0.89 ± 0.1402 | 0.83 ± 0.2161 | 0.4 | |
Right anterior cerebral artery | ||||
Mean blood flow velocity (cm/s) | 47.90 ± 11.82 | 49.18 ± 13.00 | 0.8 | |
Maximum blood flow velocity (cm/s) | 75.97 ± 16.73 | 74.53 ± 25.22 | 0.9 | |
Pulsatility index | 0.89 ± 0.11 | 0.84 ± 0.21 | 0.4 | |
Left anterior cerebral artery | ||||
Mean blood flow velocity (cm/s) | 48.95 ± 11.69 | 47.29 ± 16.57 | 0.8 | |
Maximum blood flow velocity (cm/s) | 76.66 ± 15.13 | 70.61 ± 25.79 | 0.5 | |
Pulsatility index | 0.87 ± 0.15 | 0.89 ± 0.23 | 0.8 | |
Right posterior cerebral artery | ||||
Mean blood flow velocity (cm/s) | 40.93 ± 8.22 | 37.80 ± 11.11 | 0.4 | |
Maximum blood flow velocity (cm/s) | 64.85 ± 13.19 | 53.55 ± 18.00 | 0.1 | |
Pulsatility index | 0.8897 ± 0.23 | 0.7651 ± 0.20 | 0.2 | |
Left posterior cerebral artery | ||||
Mean blood flow velocity (cm/s) | 37.84 ± 5.12 | 37.60 ± 10.11 | 0.9 | |
Maximum blood flow velocity (cm/s) | 59.41 ± 7.48 | 56.25 ± 17.09 | 0.5 | |
Pulsatility index | 0.86 ± 0.13 | 0.83 ± 0.20 | 0.8 | |
Basilar artery | ||||
Mean blood flow velocity (cm/s) | 41.60 ± 8.14 | 45.38 ± 12.90 | 0.4 | |
Maximum blood flow velocity (cm/s) | 65.35 ± 12.52 | 64.02 ± 25.69 | 0.8 | |
Pulsatility index | 0.86 ± 0.13 | 0.78 ± 0.20 | 0.3 |