From: Autoimmune causes of encephalitis syndrome in Thailand: prospective study of 103 patients
Clinical course & investigations | NMDA | Demyelinating diseases/NMO | AMPA | Behcet | ANNA2 (anti-Ri) | GABA | NMDA+ANNA2 | VGKC | Anti-Yo | NPLE |
---|---|---|---|---|---|---|---|---|---|---|
Encephalitis: myelitis | 4: 1 | 1: 2 | 0: 1 | 0: 1 | 5: 1 | 1: 0 | 1: 0 | 1: 0 | 2: 0 | 3: 1 |
Average age (yr) | 39 | 52 | 2 | 33 | 67 | 70 | 18 | 67 | 16 | 31 |
(5–43) | (8–56) | (25–82) |  | (11–21) | (23–50) | |||||
Female: male | 4: 1 | 3: 0 | 1: 0 | 2: 0 | 3: 3 | 0: 1 | 0: 1 | 0: 1 | 1: 1 | 4: 0 |
Underlying disease | ovarian teratoma (1) | - | - | - | DM(1), SLE(1) Ovarian cancer (1) | alcoholic cirrhosis | hemophagocytic syndrome | DM | Germ cells tumor (1) | SLE (4) |
Prodrome symptoms | headache (2), fever (1) | fever (1) | fever with rash | - | fever (2), URI (1), | - | fever | fever + headache | fever (1), headache (1) | fever (2), weight loss (1), fatigue + rash + alopecia (1) |
anorexia (1) | ||||||||||
Presenting symptoms | psychosis + seizure (3), behavior change (1), quadripa resis (1) | behavior change ± Seizure (2), drowsy (1) parkinsonism (1) | stiff person | para paresis | psychosis ± seizure (2), Seizure (3), para paresis (1) | behavior change + Seizure (1) | seizure (1) | behavior change + Seizure (1) | behavior change (1), seizure (1) | behavior change (1), psychosis (1), seizure (1), paraparesis (1) |
Average | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
CSF wbc | 32 | 5 | 0 | 157 | 1 | 0 | 0 | 0 | 30 | 0 |
(cells/mm3) | (0–62) | (5–60) |  |  | (0–19) |  |  |  | (0–60) | (0–1) |
Average CSF protein | 30 | 45 | 22 | 55 | 40 | 36 | 58 | 51 | 43 | 99 |
(mg/dl) | (19–242) | (30–66) | (2–68) | (42–45) | (28–142) | |||||
Average CSF sugar (mg/dl) | 62 | 73 | 59 | 40 | 83 | 71 | 53 | 149 | 70 | 65 |
(44–102) | (27–104) | (50–95) | (67–73) | (47–82) | ||||||
Imaging pattern | normal (1), meninges (1), multifocal (2) | white matter (1), brainstem + midline (1) | normal | myelo pathy | non-specific change (2), temporal lobe (2), multiple cortical lesions (1) | white matter (1) | cerebral atrophy(1) | meninges + cortex (1) | non-specific white matter change (1), miscellenous (1) | midline + cortex (1), non-specific white matter change (1) |
Outcome | complete recovered (1), partially recovered | partially recovered (1), disable (2) | partially recovered, | disable | partially recovered (4), Disable (3) | dead | partially recovered | partially recovered | partially recovered (2) | partially recovered (1), disable (2), dead (1) |
 | (1), disable (3) |  |  |  |  |  |  |  |  |  |