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Table 2 Characteristics of studies included in this systematic review

From: The association between cognitive function and white matter lesion location in older adults: a systematic review

Reference

Sample size

Study design

Publishing year

Sample characteristics

Groot et al. [24]

1077

Cross-Sectional

2000

Subsample of Rotterdam and Zeotemeer Studies

Shenkin et al. [25]

105

Cross-Sectional

2005

Random Sample of Community-Dwelling Participants

Baune et al. [26]

268

Cross-Sectional

2009

Subsample of MEMO Study

Kim et al. [27]

84

Cross-Sectional

2011

Random Sample of Normals/Recruited from Memory Clinic

Silbert et al. [28]

104

Longitudinal

2008

Subsample of Oregon Brain Aging Study

McClleland et al. [21]

3647

Cross-Sectional

2000

Subsample of CHS Cohort

Wright et al. [29]

656

Cross-Sectional

2008

Subsample of NOMAS Cohort study

Kaplan et al. [30]

95

Cross-Sectional

2009

Random Sample of Participants

Wakefield et al. [31]

99

Cross-Sectional

2010

Sample Selected for a Longitudinal Study

O’Brien et al. [32]

149

Cross-Sectional

2002

Subsample of SCOPE Study

Smith et al. [14]

145

Cross-Sectional

2011

Subsample of Prospective Study

Burns et al. [33]

156

Cross-Sectional

2005

88 Normal (CDR=0), 68 Early-Stage AD (CDR=0.5,1)

Ishii et al. [34]

453

Cross-Sectional

2007

340 (CDR=0), 113 (CDR=0.5)

Tullberg et al. [35]

78

Cross-Sectional

2004

22 Normal (CDR=0), 30 CIND (CDR=0.5), 26 Demented (CDR≥1)

 
  1. Abbreviations: MEMO = Memory and Morbidity in Augsburg Elderly; CDR = Clinical Dementia Rating Scale; CHS = Cardiovascular Health Study; NOMAS = Northern Manhattan Study; SCOPE = Study on Cognition and Prognosis in Elderly; CIND = Cognitively Impaired not Demented.