Figure 2From: Free radical scavenger, edaravone, reduces the lesion size of lacunar infarction in human brain ischemic stroke Alteration of the lesion size by different stroke subtypes. Scatter graphs of the ratios (T2WI/DWI) of edaravone(-) group (open circle) and edaravone(+) group (closed circle) in cardioembolism (A), large-artery atherosclerosis (C) and small-vessel occlusion (E) stroke subtypes. Average ratios of edaravone(-) group (white bar) and edaravone(+) group (black bar) in the cardioembolism (B), the large-artery atherosclerosis (D) and the small-vessel occlusion (F). Number of cases is indicated in the bar. The regression lines indicate in dotted line as edaravone(-) group and in black line as edaravone(+) group (the formula of cardioembolism: y = 1.07-0.14x, R2 = 0.53, p = 0.160 and y = 0.82-0.004x, R2 = 0.003, p = 0.786, respectively; the formula of large-artery atherosclerosis: y = 1.10-0.03x, R2 = 0.14, p = 0.028 and y = 0.81-0.01x, R2 = 0.03, p = 0.205, respectively; the formula of small-vessel occlusion: y = 1.18-0.32x, R2 = 0.14, p = 0.054 and y = 0.68-0.02x, R2 = 0.20, p = 0.007, respectively). In the small-vessel occlusion, the reduction of lesion size is earlier in edaravone(+) group compared with edaravone(-) group. There are significant differences of the average ratios between edaravone(-) and edaravone(+) groups in 1-2 months and 7-12 months in the small-vessel occlusion. *: p < 0.05 and **: p < 0.01.Back to article page