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Table 3 Associations of hemorrhage size with TNF- α genotypes in patients with spontaneous deep intracerebral hemorrhage (SDICH)

From: Association of TNF-α gene with spontaneous deep intracerebral hemorrhage in the Taiwan population: a case control study

 

Males

Females

Total

SNP

Hemorrhage size (cm3)

P-Value

Hemorrhage size (cm3)

P-Value

P-Value

T-1031C

 

0.57

 

0.23

0.27

TT

18.5 ± 2.1

 

12.0 ± 2.2

  

TC

17.4 ± 2.3

 

14.8 ± 2.5

  

CC

15.1 ± 5.3

 

-

  

C-863A

 

0.66

 

0.15

0.31

CC

18.2 ± 2.0

 

11.9 ± 2.1

  

CA

18.2 ± 2.7

 

15.9 ± 2.7

  

AA

15.7 ± 5.3

 

2.0 ± 0

  

C-857T

 

0.04

 

0.58

0.23

CC

18.9 ± 1.9

 

12.6 ± 2.3

  

CT

15.5 ± 2.6

 

14.1 ± 2.4

  

TT

3.5 ± 0.5

 

2.0 ± 0

  

G-308A

 

0.80

 

0.95

0.84

GG

18.3 ± 2.0

 

13.2 ± 1.7

  

GA

17.8 ± 2.5

 

12.6 ± 5.1

  

AA

11.6 ± 3.9

 

15.0 ± 0

  
  1. GLM models that included age, sex, BMI, hypertension, TC level, and alcohol use in an additive model. Data are expressed as mean ± SE.
  2. P-values in bold were empirical p-values that estimated by permutation of 1000 replicates.