Evaluation of the middle cerebral artery occlusion techniques in the rat by in-vitro 3-dimensional micro- and nano computed tomography

Table 1 Macrospheres versus Suture Technique.

		Number of Macrospheres	Vessel Diameter (μm)	Macrosphere Diameter (μm)	Occluded Vessel Territories	Collaterals via	Vascular Volume (mm³)
Macrospheres	Anterior Cerebral Artery	7	186 ± 6*	334 ± 11	No	Contralateral Hemisphere	10.9 ± 0.9
	Middle Cerebral Artery	7	203 ± 13	335 ± 7	Partial	Thalamo-striatal Arteries	5.5 ± 1.3*
	Posterior Cerebral Artery	5	175 ± 11*	333 ± 4	No	Contralateral Hemisphere	11.4 ± 0.9
	Circle of Willis	16	205 ± 16	333 ± 8	Partial	Unknown	8.2 ± 0.8
Suture	Occluded Hemisphere				Partial	Unknown	4.02 ± 1.6*
	Non-Occluded Hemisphere				No		11.5 ± 1.1
Controls							11.6 ± 1.2

The vessel diameter shows significant differences between the anterior and posterior versus the middle cerebral artery and the circle of Willis (* p < 0.002). The macrosphere diameter is not related to the occluded vessel diameter (p < 0.2) but the diameter of the macrospheres shows significantly higher values than the occluded vessel (p < 0.001). Macrospheres in the middle cerebral artery showing the same vascular volume fraction as the suture technique.

ISSN: 1471-2377