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Cerebrovascular disease and stroke

Section edited by Szatmari Szabolcs

This section is dedicated to covering all aspects of stroke and cerebrovascular diseases. Topics of interest include, but are not limited to, ischemic stroke, spontaneous intracranial bleeding, sinus thrombosis, carotid or vertebral artery disease, cerebrovascular physiology, and neuroimaging related to cerebrovascular diseases.

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  1. Idiopathic hypereosinophilic syndrome (IHES) is associated with various organ system dysfunctions. Neurologic abnormalities have been previously noted in this syndrome. Cerebral infarction secondary to occlusi...

    Authors: Quan-Fu Li, Qing Zhang, Yue-Fang Huang and Zheng-Xiang Zhang

    Citation: BMC Neurology 2020 20:361

    Content type: Case report

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  2. The novel coronavirus (COVID-19) global pandemic is associated with an increased incidence of acute ischemic stroke (AIS) secondary to large vessel occlusion (LVO). The treatment of these patients poses unique...

    Authors: Ossama Yassin Mansour, Amer M. Malik and Italo Linfante

    Citation: BMC Neurology 2020 20:358

    Content type: Case report

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  3. Moyamoya-like vasculopathy (MMV) and myosin heavy chain 9-related platelet disorders (MYH9-RPDs) or macrothrombocitopenias are rare syndromes. Their association is even more infrequent.

    Authors: Athena Cristina Ribigan, Raluca Stefania Badea, Alida Ciocan, Dana Stefan, Bogdan Casaru, Patricia Ioan, Florina Antochi and Ovidiu Băjenaru

    Citation: BMC Neurology 2020 20:352

    Content type: Case report

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  4. Oculomotor nerve palsy (ONP) is a common symptom of posterior communicating artery aneurysm (PcomAA) that can lead to impaired eye movement and pupil dilation. Currently, surgical clipping and endovascular emb...

    Authors: Li-qiang Tian and Qing-xi Fu

    Citation: BMC Neurology 2020 20:351

    Content type: Research article

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  5. Stroke is a major cause of disability and stroke incidence increases with age. Stroke frequently results in permanent limitations of mobility, and, consequently, the need for the help of others in activities o...

    Authors: R. Rössler, S. A. Bridenbaugh, S. T. Engelter, R. Weibel, D. Infanger, E. Giannouli, A. Sofios, L. Iendra, E. Portegijs, T. Rantanen, L. Streese, H. Hanssen, R. Roth, A. Schmidt-Trucksäss, N. Peters and T. Hinrichs

    Citation: BMC Neurology 2020 20:348

    Content type: Study protocol

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  6. Hashimoto’s disease has reportedly been associated with stroke; however, cerebrovascular morphology and clinical course remain poorly documented. The present study aimed to determine the angiographic features ...

    Authors: Eika Hamano, Masaki Nishimura, Hisae Mori, Tetsu Satow and Jun C. Takahashi

    Citation: BMC Neurology 2020 20:345

    Content type: Research article

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  7. Previous studies have shown that a single Coma-Recovery Scale-Revision (CRS-R) assessment can identify high rates of misdiagnosis by clinical consensus. The aim of this study was to investigate the proportion ...

    Authors: Jing Wang, Xiaohua Hu, Zhouyao Hu, Ziwei Sun, Steven Laureys and Haibo Di

    Citation: BMC Neurology 2020 20:343

    Content type: Research article

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  8. Carotid occlusive disease is a type of progressive disease resulting in ischemic stroke. Extracranial-intracranial bypass surgery represents a valid therapeutic option when medical treatment does not make effe...

    Authors: Yin Li, Yu-yu Wei, Yang Cao, Xiao-yang Lu, Yuan Yao and Lin Wang

    Citation: BMC Neurology 2020 20:335

    Content type: Case report

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  9. Common carotid artery occlusive disease (CCAOD) could form internal carotid artery steal pathways. Based on the diagnostic results of digital subtraction angiography (DSA), head and neck computed tomography an...

    Authors: Dongxu Wang, Zheng Li, Xiaoyang Zheng, Houyi Cong, Tianyu Zhang, Zhenghua Wang, Yuguang Wang and Jun He

    Citation: BMC Neurology 2020 20:334

    Content type: Research article

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  10. It is unknown whether microangiopathic ischemic strokes outside the visual pathway go along with subclinical changes of the retinal structure or the visual system. The objectives of this prospective non-interv...

    Authors: John-Ih Lee, Lena Gemerzki, Margit Weise, Laura Boerker, Jonas Graf, Lea Jansen, Rainer Guthoff, Orhan Aktas, Michael Gliem, Sebastian Jander, Hans-Peter Hartung and Philipp Albrecht

    Citation: BMC Neurology 2020 20:333

    Content type: Research article

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  11. Susceptibility weighted imaging (SWI) provides an approximate assessment of tissue perfusion and shows prominent hypointense cortical veins in the ischemic territory because of the increased concentration of d...

    Authors: Wei Li, Wei-Min Xiao, Gen-Pei Luo, Yong-Lin Liu, Jian-Feng Qu, Xue-Wen Fang, Fang Wang and Yang-Kun Chen

    Citation: BMC Neurology 2020 20:331

    Content type: Research article

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  12. Infections could increase the risk of poor outcome in patients with acute ischemic stroke (AIS). The peripheral neutrophil-to-lymphocyte ratio (NLR) is an important indicator of inflammation. The purpose of ou...

    Authors: Lanying He, Jian Wang, Feng Wang, Lili Zhang, Lijuan Zhang and Wang Zhao

    Citation: BMC Neurology 2020 20:328

    Content type: Research article

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  13. Mechanical thrombectomy was approved by NICE as a treatment for stroke in 2016. However, most of the evidence is from studies conducted during working hours. Only few centres in the UK perform thrombectomies o...

    Authors: Jake Weddell, Emma Parr, Stacey Knight, Girish Muddegowda, Indira Natarajan, Jayan Chembala, Phillip Ferdinand, Nasar Ahmad, Zoltan Pencz, Saad Rana, Anushka Warusevitane, Changez Jadun, Sanjeev Nayak, Zafar Hashim, Albin Augustine, Julius Sim…

    Citation: BMC Neurology 2020 20:326

    Content type: Research article

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  14. Cognitive impairment in adult moyamoya disease (MMD) is thought to be the result of ischemic stroke; however, the presence and extent of cognitive decline in asymptomatic patients is unclear.

    Authors: Shihao He, Ran Duan, Ziqi Liu, Xun Ye, Li Yuan, Tian Li, Cunxin Tan, Junshi Shao, Shusen Qin and Rong Wang

    Citation: BMC Neurology 2020 20:322

    Content type: Research article

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  15. Thalamic blood supply consists of four major vascular territories. Out of them paramedian arteries supply ipsilateral paramedian thalami and occasionally rostral mid brain. Rarely both paramedian arteries aris...

    Authors: K. M. I. U. Ranasinghe, H. M. M. T. B. Herath, D. Dissanayake and M. Seneviratne

    Citation: BMC Neurology 2020 20:320

    Content type: Case report

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  16. Current guidelines recommend measurement of troponin in acute ischemic stroke (AIS) patients. In AIS patients, troponin elevation is associated with increased mortality and worse outcome. However, uncertainty ...

    Authors: Christian H. Nolte, Regina von Rennenberg, Simon Litmeier, Jan F. Scheitz, David M. Leistner, Stephan Blankenberg, Martin Dichgans, Hugo Katus, Gabor C. Petzold, Burkert Pieske, Vera Regitz-Zagrosek, Karl Wegscheider, Andreas M. Zeiher, Ulf Landmesser and Matthias Endres

    Citation: BMC Neurology 2020 20:318

    Content type: Study protocol

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  17. Hereditary hemorrhagic telangiectasia (HHT), also known as Rendu-Osler-Weber syndrome, is a rare disorder characterized by recurrent epistaxis, telangiectasias and systemic arteriovenous malformations (AVMs). ...

    Authors: Davide Villa, Claudia Cinnante, Gloria Valcamonica, Giulia Manenti, Silvia Lanfranconi, Annalisa Colombi, Isabella Ghione, Maria Cristina Saetti, Mario D’Amico, Sara Bonato, Nereo Bresolin, Giacomo Pietro Comi and Dario Ronchi

    Citation: BMC Neurology 2020 20:316

    Content type: Case report

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  18. Kartagener syndrome is an autosomal recessive inherited disorder of primary ciliary dyskinesia. Moyamoya syndrome refers to a moyamoya angiopathy associated with other neurological and/or extra-neurological sy...

    Authors: Lili Zhang, Xungang Feng, Junhu Zhang, Yanlei Hao and Yuzhong Wang

    Citation: BMC Neurology 2020 20:314

    Content type: Case report

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  19. Stroke increases the risk of cognitive impairment even several years after the stroke event. The exact mechanisms of post-stroke cognitive decline are unclear, but the immunological response to stroke might pl...

    Authors: Lauren L. Drag, Michael Mlynash, Huda Nassar, Elizabeth Osborn, Da E. Kim, Martin S. Angst, Nima Aghaeepour, Marion Buckwalter and Maarten G. Lansberg

    Citation: BMC Neurology 2020 20:313

    Content type: Study protocol

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  20. The morbidity and mortality of stroke is disproportionately high in developing countries owing to the poor health care system and poor neurologic interventions. Though a number of studies were conducted to est...

    Authors: Muluneh Alene, Moges Agazhe Assemie, Leltework Yismaw and Daniel Bekele Ketema

    Citation: BMC Neurology 2020 20:309

    Content type: Research article

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  21. The present study aims to evaluate the performance and the clinical applicability of the Recognition of Stroke in the Emergency Department (ROSIER) scale via systematic review and meta-analysis.

    Authors: Fei Han, Chao Zuo and Guodong Zheng

    Citation: BMC Neurology 2020 20:304

    Content type: Research article

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  22. Ischemic Moyamoya disease is one of the important causes of stroke, which leads to severe impairment in cognitive functions. This cognitive impairment occurs prior to stroke. However, the cognitive functions t...

    Authors: Ziqi Liu, Shihao He, Zongsheng Xu, Ran Duan, Li Yuan, Chu Xiao, Zhe Yi and Rong Wang

    Citation: BMC Neurology 2020 20:302

    Content type: Research article

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  23. The evidence on the efficacy of adipose derived stem cells (ADSCs) in the treatment of stroke is controversial. Therefore, the aim of present systematic review and meta-analysis is to evaluate the efficacy of ...

    Authors: Mahmoud Yousefifard, Jebreil Shamseddin, Asrin Babahajian and Arash Sarveazad

    Citation: BMC Neurology 2020 20:294

    Content type: Research article

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  24. New evidence on the efficacy and safety of dual antiplatelet therapy for secondary stroke prevention have been realized in the recent years. An updated meta analysis was done to determine the effect of the var...

    Authors: Christessa Emille Que Albay, Frederick Gavril D. Leyson and Federick C. Cheng

    Citation: BMC Neurology 2020 20:224

    Content type: Research article

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    The Retraction Note to this article has been published in BMC Neurology 2020 20:447

  25. Atherosclerosis of the internal carotid artery (ICA) is an important cause of ischemic stroke. Artery-to-artery embolism is the major stroke mechanism in patients with atherosclerotic carotid disease. This stu...

    Authors: Ho Geol Woo, Sung Hyuk Heo, Eui Jong Kim, Dae-il Chang, Tae Jin Song and Bum Joon Kim

    Citation: BMC Neurology 2020 20:288

    Content type: Research article

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  26. To evaluate the medium-and long-term effect of intravascular interventional therapy for symptomatic severe basilar artery stenosis supported by multimodal imaging.

    Authors: Yuanzhi Li, Zhenfa Li, Ligang Song, Weimin Xie, Xianghao Gong, Dongliang He and Xin Zhang

    Citation: BMC Neurology 2020 20:289

    Content type: Research article

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  27. Surgical treatment of anterior communicating artery (Acom) aneurysm is challenging due to anatomic complexity. We aimed to describe our experiences with endovascular treatment (EVT) of Acom aneurysms, and to ev.....

    Authors: Chang Ki Jang, Joonho Chung, Jae Whan Lee, Seung Kon Huh, Nak-Hoon Son and Keun Young Park

    Citation: BMC Neurology 2020 20:287

    Content type: Research article

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  28. Patients with vascular Ehlers-Danlos syndrome (EDS) occasionally suffer from arterial dissection. Eagle syndrome, which is caused by an elongated styloid process and also causes arterial dissection, is difficu...

    Authors: Hajime Ikenouchi, Masahito Takagi, Ayako Nishimura, Eriko Yamaguchi, Junpei Koge, Kozue Saito, Kazunori Toyoda and Masatoshi Koga

    Citation: BMC Neurology 2020 20:285

    Content type: Case report

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  29. Compared with embolic occlusions, intracranial atherosclerotic stenosis (ICAS)-related large vessel occlusions (LVOs) often require rescue treatment following mechanical thrombectomy (MT). Herein, we hypothesi...

    Authors: Yong-Won Kim, Sung-Il Sohn, Joonsang Yoo, Jeong-Ho Hong, Chang-Hyun Kim, Dong-Hun Kang, Yong-Sun Kim, Seong-Joon Lee, Ji Man Hong, Jin Wook Choi, Yang-Ha Hwang and Jin Soo Lee

    Citation: BMC Neurology 2020 20:284

    Content type: Research article

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  30. Although stent retriever (SR) is recommended as a frontline device of endovascular treatment (EVT) for embolic large artery occlusion causing acute ischemic stroke, contact aspiration (CA) device showed simila...

    Authors: Joonsang Yoo, Seong-Joon Lee, Jeong-Ho Hong, Yong-Won Kim, Ji Man Hong, Chang-Hyun Kim, Dong-Hun Kang, Jin Wook Choi, Yong-Sun Kim, Sung-Il Sohn, Yang-Ha Hwang and Jin Soo Lee

    Citation: BMC Neurology 2020 20:283

    Content type: Research article

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  31. Ischemic stroke is a leading cause of morbidity and mortality. Thrombolytic therapy improves disability and survival rates; however, to be effective, it must be given within 4.5 h of onset. Moreover, thromboly...

    Authors: Jun Ni, Huisheng Chen, Guofang Chen, Yong Ji, Fei Yi, Zhuobo Zhang, Yi Yang, Jin Wu, Xueli Cai, Bei Shao, Jianfeng Wang, Yafang Liu, Deqin Geng, Xinhui Qu, Xiaohong Li, Yan Wei…

    Citation: BMC Neurology 2020 20:282

    Content type: Research article

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  32. Cerebral-cardiac syndrome, newly developed cardiac damage manifestations subsequent to cerebral injuries, is a common complication of stroke and leads to increased morbidity and mortality. The current study is...

    Authors: Haijuan Lian, Xiaomeng Xu, Xuhui Shen, Jinhua Chen, Dandan Mao, Yan Zhao and Meiqi Yao

    Citation: BMC Neurology 2020 20:272

    Content type: Research article

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  33. Cerebral vasospasm still results in high morbidity and mortality rates in patients after aneurysmal subarachnoid hemorrhage (SAH). The aim of this study was to establish a protocol for the management of vasosp...

    Authors: Chun-Ting Chen, Ching-Chang Chen, Alvin Yi-Chou Wang, Yi-Ming Wu, Shy-Chyi Chin, Po-Chuan Hsieh, Mun-Chun Yeap, Shih-Yuan Hsu and Ya-Jui Lin

    Citation: BMC Neurology 2020 20:271

    Content type: Research article

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  34. Stroke mimics account for up to one-third of acute stroke admissions and are a heterogeneous entity which pose diagnostic challenges. Diagnosing such patients is however crucial to avoid delays in treatment an...

    Authors: Sarah Shali Matuja, Khuzeima Khanbhai, Karim M. Mahawish and Patricia Munseri

    Citation: BMC Neurology 2020 20:270

    Content type: Research article

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  35. Acute ischemic stroke is a time-sensitive emergency where accurate diagnosis is required promptly. Due to time pressures, stroke mimics who present with similar signs and symptoms as acute ischemic stroke, pos...

    Authors: Tian Ming Tu, Guan Zhong Tan, Seyed Ehsan Saffari, Chee Keong Wee, David Jeremiah Ming Siang Chee, Camlyn Tan and Hoon Chin Lim

    Citation: BMC Neurology 2020 20:269

    Content type: Research article

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  36. Remote ischemic conditioning during cerebral ischemia (remote ischemic perconditioning, RIPerC) refers to the application of several cycles of brief ischemia and reperfusion (I/R) commonly to a limb, and it re...

    Authors: Francisco Purroy, Cristina García, Gerard Mauri, Cristina Pereira, Coral Torres, Daniel Vazquez-Justes, Mikel Vicente-Pascual, Ana Vena and Gloria Arque

    Citation: BMC Neurology 2020 20:266

    Content type: Research article

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  37. Level of dependency after a stroke is important for long-term outcome in several aspects, but less is known about important predictors for outcome depending on functional dependency. The aim of the current stu...

    Authors: Emma Westerlind, Daniel Hörsell and Hanna C. Persson

    Citation: BMC Neurology 2020 20:263

    Content type: Research article

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  38. Delayed cerebral ischemia is one of the leading causes of death and disability in patients with subarachnoid hemorrhage (SAH). Transluminal balloon angioplasty (TBA) is a therapeutic option for vasospasms affe...

    Authors: Ioannis Tsogkas, Vesna Malinova, Katharina Schregel, Dorothee Mielke, Daniel Behme, Veit Rohde, Michael Knauth and Marios-Nikos Psychogios

    Citation: BMC Neurology 2020 20:260

    Content type: Research article

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  39. Deep vein thrombosis (DVT) is an important complication of ischemic stroke, although the incidence of DVT is regarded as being lower in Asian than in non-Asian patients. Here, we investigated the incidence and...

    Authors: Sang Hee Ha, Yeon-Jung Kim, Sung Hyuk Heo, Dae-il Chang and Bum Joon Kim

    Citation: BMC Neurology 2020 20:257

    Content type: Research article

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  40. Stroke is a leading cause of long-term disability. Cost-effective post-stroke rehabilitation programs for upper limb are critically needed. Brain-Computer Interfaces (BCIs) which enable the modulation of Elect...

    Authors: Donatella Mattia, Floriana Pichiorri, Emma Colamarino, Marcella Masciullo, Giovanni Morone, Jlenia Toppi, Iolanda Pisotta, Federica Tamburella, Matteo Lorusso, Stefano Paolucci, Maria Puopolo, Febo Cincotti and Marco Molinari

    Citation: BMC Neurology 2020 20:254

    Content type: Study protocol

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  41. High adherence to a Mediterranean Diet is associated with reduced incidence and mortality of acute ischemic stroke (AIS) but may also be associated with severity. Our purpose was to investigate the association...

    Authors: Pablo M. Lavados, Enrico Mazzon, Alexis Rojo, Alejandro M. Brunser and Verónica V. Olavarría

    Citation: BMC Neurology 2020 20:252

    Content type: Research article

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  42. The purpose of this study was to clarify the effect of asymmetric COW variants on carotid flow changes, and proposed an easy estimate of the representative carotid flow volume for accurate numerical simulation.

    Authors: Te-Chang Wu, Tai-Yuan Chen, Ching-Chung Ko, Jeon-Hor Chen and Ching-Po Lin

    Citation: BMC Neurology 2020 20:251

    Content type: Research article

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  43. Post-stroke depression (PSD) is a mood disorder characterized by depression and anhedonia caused by stroke. Metabolomics identified metabolites associated with PSD, but previous studies are based on gas chroma...

    Authors: Man Wang, Xianwei Gui, Lanxiang Wu, Sheng Tian, Hansen Wang, Liang Xie and Wei Wu

    Citation: BMC Neurology 2020 20:250

    Content type: Research article

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  44. Cerebral venous sinus thrombosis (CVST), a rare cause of cerebral infarction, is often unrecognized at initial presentation. We report the case of a patient with bilateral corpus callosum and corona radiata in...

    Authors: Rui Lan, Yun-zhi Ma, Xiao-ming Shen, Ji-tao Wu, Chun-qing Gu and Yong Zhang

    Citation: BMC Neurology 2020 20:249

    Content type: Case report

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  45. Thrombolysis with recombinant tissue plasminogen activator (rtPA) improves outcome for patients with acute ischemic stroke (AIS), but many of them still have substantial disability. Glibenclamide (US adopted n...

    Authors: Kaibin Huang, Zhong Ji, Yongming Wu, Yunqiang Huang, Guangning Li, Saijun Zhou, Zhi Yang, Wenguo Huang, Guoshuai Yang, Guohu Weng, Pingyan Chen and Suyue Pan

    Citation: BMC Neurology 2020 20:239

    Content type: Study protocol

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  46. Partially thrombosed giant aneurysms at the basilar apex (BA) artery are challenging lesions with a poor prognosis if left untreated. Here we describe a rare case of extensive brain edema after growth of a sur...

    Authors: Daniel García-Pérez, Irene Panero, Carla Eiriz, Luis Miguel Moreno, Pablo M. Munarriz, Igor Paredes, Alfonso Lagares and José F. Alén

    Citation: BMC Neurology 2020 20:232

    Content type: Case report

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  47. Arterial thoracic outlet syndrome is a rare condition characterized by a subclavian artery pathology associated with a bone abnormality. It is rarely associated with thromboembolic stroke. The mechanism of cer...

    Authors: Adam Celier, Simon Chabay, Aurélien Maurizot, Frédéric Cochennec, Daniela Stanciu and Fernando Pico

    Citation: BMC Neurology 2020 20:229

    Content type: Case report

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