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Table 2 Common KEGG pathways in different cell types of AD brain

From: Cell type-specific potential pathogenic genes and functional pathways in Alzheimer’s Disease

Pathways

Cell types

Estrogen signaling pathway

Mic, Astro, Oligo, Neuron (In), Endo

MAPK signaling pathway

Mic, Astro, Neuron (Ex), Endo

Ribosome

Mic, Oligo, Neuron (Ex)

Glutamatergic synapse

Astro, Oligo, Neuron (Ex)

Axon guidance

Astro, Oligo, Endo

Oxidative phosphorylation

Oligo, Neuron (Ex), Neuron (In)

Long-term potentiation

Oligo, Neuron (Ex), Neuron (In)

Alzheimer's disease

Oligo, Neuron (Ex), Neuron (In)

Parkinson's disease

Oligo, Neuron (Ex), Neuron (In)

Huntington's disease

Oligo, Neuron (Ex), Neuron (In)

Phagosome

Mic, Astro

HIF-1 signaling pathway

Mic, Endo

PI3K-Akt signaling pathway

Mic, Endo

Antigen processing and presentation

Mic, Endo

Mineral absorption

Astro, Endo

cAMP signaling pathway

Oligo, Neuron (In)

Protein processing in ER

Astro, Oligo

Gap junction

Astro, Neuron (Ex)

Rap1 signaling pathway

Neuron (In), Endo

  1. Mic: Microglia; Astro: Astrocytes; Oligo: Oligodendrocytes; Neuron (Ex): Excitatory neurons; Neuron (In): Inhibitory neurons; Endo: Endothelial cells