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Table 2 Effect of patient- and clinical determinants on door-to-needle time, expressed in odds ratio’s (with 95th confidence intervals) for different cut-off points

From: Determinants of extended door-to-needle time in acute ischemic stroke and its influence on in-hospital mortality: results of a nationwide Dutch clinical audit

 

Door-to-needle time

Univariate analysis

Multivariable analysis

Cut-off point in minutes

Median

90th percentile

Mediana

90th percentileb

26

55

26

55

Age (years)

 

< 50

1.19 (1.01–1.40)c

1.42 (1.11–1.81) c

1.16 (0.98–1.37)

1.38 (1.07–1.76) d

50–75

Reference

> 75

1.12 (0.98–1.27)

1.18 (0.95–1.45)

1.11 (0.97–1.27)

1.21 (0.97–1.49)

Female sex

1.21 (1.11–1.32) c

1.08 (0.94–1.24)

1.17 (1.05–1.31)d

Onset-to-door time (minutes)

< 40

1.10 (0.99–1.23)

1.42 (1.20–1.66) c

1.15 (1.00–1.33)

1.37 (1.11–1.69) d

 

40–180

Reference

 

> 180

0.76 (0.65–0.88) c

0.40 (0.28–0.57) c

0.75 (0.61–0.91) d

0.46 (0.28–0.56) d

Admission to comprehensive stroke center

0.94 (0.86–1.03)

1.27 (1.10–1.46) c

1.26 (1.04–1.50) d

Admission during off-hours

1.15 (1.06–1.25) c

1.08 (0.95–1.24)

1.12 (1.01–1.25) d

Year of inclusion

 

2015

1.24 (1.14–1.34) c

0.97 (0.85–1.11)

1.33 (1.14–1.35) d

2016

Reference

  1. aAdjusted for age, female sex, onset-to-door time, admission during off-hours and year of inclusion. bAdjusted for age, onset-to-door time and admission to comprehensive stroke center. cP-value below 0.1. dP-value below 0.05