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Fig. 5 | BMC Neurology

Fig. 5

From: PPAR-γ promotes p38 MAP kinase-mediated endothelial cell permeability through activating Sirt3

Fig. 5

PPAR- γ inhibitor reverses Sirt3 mediated cell function in HBMEC cells. A-C, TEER measurement (a) and dextran permeability testing (b) as well as CCK-8 cell proliferation assay (c) and western blot (d) were performed in HBMEC cells to identify the roles of PPAR- γ inhibitor. (e). ***, p < 0.001 as compared to the empty vector group (Vector). #, ###, p < 0.05 or p < 0.001 as compared to the Sirt3 overexpression group (Sirt3)

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