Table 2 Receiver operation characteristic analysis using serum malondialdehyde levels at day 1, 4 and 8 of severe malignant middle cerebral artery infarction as predictor of mortality at 30 days

Cut-off of malondialdehyde (mmol/mL)

> 2.87

> 2.12

> 2.01

Sensitivity and 95% CI

58.8 (40.7–75.4)

83.3 (58.6–96.4)

83.3 (51.6–97.9)

Specificity and 95% CI

94.1 (80.3–99.3)

91.2 (76.3–98.1)

94.1 (80.3–99.3)

Positive likelihood ratio and 95% CI

10.0 (2.5–39.5)

9.4 (3.1–28.4)

14.2 (3.6–55.6)

Negative likelihood ratio and 95% CI

0.4 (0.3–0.7)

0.2 (0.1–0.5)

0.2 (0.1–0.6)

Positive predicted value and 95% CI

90.9 (71.7–97.5)

83.3 (62.5–93.8)

83.3 (56.0–95.2)

Negative predicted value and 95% CI

69.6 (60.3–77.5)

91.2 (78.5–96.7)

94.1 (81.8–98.3)