Table 3 Distribution of brain lesions and neurologic symptoms in patients with JCV-positive and JCV-negative CSF samples
| Â | Â | MRI (T2/FLAIR) lesion (%)a | Â | ||||
|---|---|---|---|---|---|---|---|
Patient | JCV DNA | Cerebral white matter | Cerebellar white matter | Brain stem | Pattern | Symmetry | Neurologic symptom |
1 | Positive | + | – | – | Bilateral | Asymmetric | Quadriplegia, Consciousness disorder, Aphasia, Involuntary movement, Increased deep tendon reflex |
2 | Positive | – | + | – | Unilateral | Asymmetric | Cerebellar symptom |
3 | Positive | + | + | – | Bilateral | Asymmetric | Hemiplegia, Mental manifestation, Dysarthria, Dysphagia, Increased deep tendon reflex |
4 | Positive | – | + | – | Unilateral | Asymmetric | Cerebellar symptom |
5 | Positive | + | – | + | Bilateral | Asymmetric | Dysarthria, Sensory disturbance, Cerebellar symptom |
6 | Positive | + | + | + | Bilateral | Asymmetric | Consciousness disorder, Mental manifestation, Aphasia, Dysarthria, Dysphagia, Sensory disturbance, Involuntary movement |
7 | Positive | + | – | – | Bilateral | Asymmetric | Consciousness disorder, Aphasia |
8 | Positivea | + | + | + | Bilateral | Asymmetric | Hemiplegia, Consciousness disorder, Increased deep tendon reflex, Cerebellar symptom |
9 | Negative | + | – | – | Unilateral | Asymmetric | Hemiplegia, Consciousness disorder, Aphasia |
10 | Negative | + | – | – | Bilateral | Asymmetric | Increased deep tendon reflex |
11 | Negative | + | – | – | Unilateral | Asymmetric | Sensory disturbance |
12 | Negative | – | – | + | Bilateral | Symmetric | Sensory disturbance |
13 | Negative | + | – | – | Bilateral | Symmetric | Consciousness disorder, Mental manifestation |
14 | Negative | + | – | – | Bilateral | Symmetric | Consciousness disorder |
15 | Negative | + | – | – | Bilateral | Asymmetric | Consciousness disorder, Dysarthria |
16 | Negative | + | – | + | Bilateral | Asymmetric | Consciousness disorder, Sensory disturbance |
17 | Negative | + | + | – | Bilateral | Symmetric | Quadriplegia, Consciousness disorder |
18 | Negative | + | + | + | Bilateral | Symmetric | Dysarthria, Cerebellar symptom |
19 | Negative | + | + | + | Bilateral | Symmetric | Consciousness disorder, Dysarthria, Sensory disturbance, Increased deep tendon reflex, Cerebellar symptom |
20 | Negative | + | – | – | Bilateral | Symmetric | Consciousness disorder, visual disturbance, Dysarthria, Dysphagia, Sensory disturbance |