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Table 1 Comparison of baseline characteristics between patients with no prestroke statins use prestroke statins use groups

From: Prestroke statins use reduces oxidized low density lipoprotein levels and improves clinical outcomes in patients with atrial fibrillation related acute ischemic stroke

 

No prestroke statins use group (136)

Prestroke Statins use group (106)

OR(95% CI)

P*

Age, y (Mean SD)

66.1 ± 10.5

67.2 ± 9.9

 

0.303

NIHSS score, median (IQR)

11 (7–14)

8(6–12)

 

0.041

Mean AF duration, m (Mean SD)

67.7 ± 10.0

67.8 ± 11.3

 

0.915

CHA2DS2-VASc, median (IQR)

4(3–5)

4(3–5)

 

0.090

Females, n (%)

66 (48.5%)

58 (54.7%)

1.29 (0.77–2.13)

0.339

Men, n (%)

70 (51.5%

48 (45.3%)

1.29 (0.77–2.13)

0.339

BMI ≥ 24 kg/m, n (%)

36 (26.5%)

37 (34.9%)

1.50 (0.86–2.59)

0.156

Hypertension, patients, n (%)

90 (66.8%)

79 (74.5%)

1.50 (0.85–2.63)

0.160

Current Smoking, n (%)

46 (33.8%)

30 (28.3%)

0.77 (0.45–1.34)

0.359

Current alcohol consumption, n (%)

41 (30.2%)

24 (22.6%)

0.67 (0.38–1.22)

0.191

Diabetes, n (%)

37 (27.2%)

31 (29.2%)

1.11 (0.63–1.94)

0.736

Hyperlipidemia, n (%)

40 (29.4%)

79 (74.5%)

7.02 (3.96–12.4)

< 0.001

AF Type

 Paroxysmal, n (%)

47(34.6)

38(35.8)

0.95(0.56–1.61)

0.835

 Permanent, n (%)

89(65.4)

68(64.2)

0.95(0.56–1.61)

0.835

 Family history of stroke, n (%)

28 (20.6%)

23 (21.7%)

1.07 (0.57–1.99)

0.834

 Ox-LDL,U/L (Mean SD)

37.6 ± 5.1

33.5 ± 5.5

 

< 0.001

Medication use

 Warfarin, n (%)

20 (14.7%)

19 (17.9%)

1.27 (0.64–2.52)

0.499

 direct oral anticoagulants, n (%)

10(7.4%)

8(7.5%)

1.03(0.39–2.70)

0.954

 antiplatelets, n (%)

25(18.4)

15(14.2)

0.73(0.36–1.45)

0.379

 Antihypertensive, n (%)

76 (55.9%)

58 ((54.7%)

0.95 (0.57–1.59)

0.856

  1. Bold indicates P-values less than 0.05
  2. *Comparison between no prestroke statins use and prestroke statins use groups. The data are presented as median values (interquartile range [IQR]), numbers (%), or mean values (±standard deviation). Categorical variables are expressed as frequency (percent) for P values. Baseline characteristics were compared between the 2 subgroups by univariate analysis using Pearson χ2, distributions of continuous variables were determined by the Kolmogorov–Smirnov test, Mann–Whitney two sample test was applied in case of non-normal distributions