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Table 3 Laboratory and MRI monitoring of interferon beta patients according to the German competence network multiple sclerosis (KKNMS) [52]

From: An update on Peginterferon beta-1a Management in Multiple Sclerosis: results from an interdisciplinary Board of German and Austrian Neurologists and dermatologists

 

Prior to IFN initiation

During IFN treatment

After 1 month of initiation

Quarterly during first year of treatment

1 year of initiation: every 6–12 months or as clinically indicated

Complete, differential blood cell & platelet counts

x

x

x

x

Liver enzyme tests (ALT, AST, GGT, bilirubin)

x

x

x

x

Renal function (creatinine, estimated creatinine clearance/GFR)

x

x

x

x

Inflammation and Infections (urine status)

x

 

TSH

 

periodically

Pregnancy test

x

 

MRI

x

annually