Table 4 Evolution of clinical outcomes over 5 years in multiple sclerosis patients, according to their baseline CCSVI status
Total (n = 90) | CCSVI CCSVI ISNVD criteria fulfilled [22] (n = 52) | CCSVI CCSVI ISNVD criteria not-fulfilled [22] (n = 38) | p value | |
|---|---|---|---|---|
EDSS at baseline, median (IQR) | 3.0 (1.5–5.5) | 3.5 (2.0–6.0) | 2.5 (1.5–4.0) | 0.08 |
EDSS at follow-up, median (IQR) | 3.5 (2.0–6.0) | 3.5 (1.7–6.5) | 3.0 (2.0–4.0) | 0.11 |
∆EDSS, mean (SD); median | 0.3 (0.9); 0.5 | 0.4 (0.7); 0.5 | 0.2 (1.0); 0.3 | 0.76 |
DP at follow-up, n (%) | 25 (28) | 16 (31) | 9 (24) | 0.50 |
Number of relapses between baseline and follow-up, mean (SD) | 0.9 (2.0) | 0.8 (1.6) | 1.0 (2.5) | 0.52 |
Annual relapse rate over the follow-up, mean (SD) | 0.2 (0.4) | 0.1 (0.3) | 0.2 (0.5) | 0.52 |
Relapse free from baseline to follow-up, n (%) | 55 (61) | 33 (64) | 22 (58) | 0.60 |